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RScore: a peptide randomicity score for evaluating tandem mass spectra
Li, FX; Sun, W; Gao, YH; Wang, J
Source PublicationRAPID COMMUNICATIONS IN MASS SPECTROMETRY
2004
Volume18Issue:14Pages:1655-1659
SubtypeArticle
AbstractRScore, a new criterion of randomicity for evaluating tandem mass (MS/MS) spectra, is described. RScore is defined as the relative quality in cross-correlation and matched intensity percentage of a potentially positive peptide to those of other possible candidates for the same spectrum. By utilizing RScore combined with less stringent SEQUEST score filters, the number of true positive peptides can be increased and the number of false positives in datasets from a known protein mixture can be reduced compared with current SEQUEST parameters used alone. This algorithm is simple and adds little overheads to SEQUEST computation. Copyright (C) 2004 John Wiley Sons, Ltd.
WOS HeadingsScience & Technology ; Physical Sciences ; Technology
WOS KeywordPROTEIN IDENTIFICATION ; SPECTROMETRY DATA ; DATABASE SEARCH ; ALGORITHM ; MS/MS
Indexed BySCI
Language英语
WOS Research AreaChemistry ; Spectroscopy
WOS SubjectChemistry, Analytical ; Spectroscopy
WOS IDWOS:000222736400017
Citation statistics
Cited Times:19[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9985
Collection09年以前成果
Affiliation1.Chinese Acad Sci, Lab Complex Syst & Intelligence Sci, Inst Automat, Beijing 100080, Peoples R China
2.Chinese Acad Med Sci, Peking Union Med Coll, Proteom Res Ctr, Natl Key Lab Med Mol Biol,Inst Basic Med Sci, Beijing 100005, Peoples R China
Recommended Citation
GB/T 7714
Li, FX,Sun, W,Gao, YH,et al. RScore: a peptide randomicity score for evaluating tandem mass spectra[J]. RAPID COMMUNICATIONS IN MASS SPECTROMETRY,2004,18(14):1655-1659.
APA Li, FX,Sun, W,Gao, YH,&Wang, J.(2004).RScore: a peptide randomicity score for evaluating tandem mass spectra.RAPID COMMUNICATIONS IN MASS SPECTROMETRY,18(14),1655-1659.
MLA Li, FX,et al."RScore: a peptide randomicity score for evaluating tandem mass spectra".RAPID COMMUNICATIONS IN MASS SPECTROMETRY 18.14(2004):1655-1659.
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