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ImmunoAIzer: A Deep Learning-Based Computational Framework to Characterize Cell Distribution and Gene Mutation in Tumor Microenvironment 期刊论文
CANCERS, 2021, 卷号: 13, 期号: 7, 页码: 21
Authors:  Bian, Chang;  Wang, Yu;  Lu, Zhihao;  An, Yu;  Wang, Hanfan;  Kong, Lingxin;  Du, Yang;  Tian, Jie
Adobe PDF(14076Kb)  |  Favorite  |  View/Download:14/0  |  Submit date:2021/05/17
deep learning  cell distribution  biomarker  tumor gene mutation  tumor microenvironment (TME)  semi-supervised learning  hematoxylin and eosin (H&  E)  
Computational Bioinformatics and Machine Learning Models to Identify the Diseasome and Neurological Disease Comorbidities 学位论文
, 中国科学院自动化研究所: 中国科学院大学, 2020
Authors:  Md Habibur Rahman
Adobe PDF(12630Kb)  |  Favorite  |  View/Download:63/1  |  Submit date:2020/07/15
疾病共病鉴定  生存分析  生物信息学  机器学习  2 型糖尿病  神经系统疾病  胶质母细胞瘤  通路  基因本体  蛋白质  
A Network-Based Bioinformatics Approach to Identify Molecular Biomarkers for Type 2 Diabetes that Are Linked to the Progression of Neurological Diseases 期刊论文
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2020, 卷号: 17, 期号: 3, 页码: 25
Authors:  Rahman, Md Habibur;  Peng, Silong;  Hu, Xiyuan;  Chen, Chen;  Rahman, Md Rezanur;  Uddin, Shahadat;  Quinn, Julian M. W.;  Moni, Mohammad Ali
View  |  Adobe PDF(2713Kb)  |  Favorite  |  View/Download:92/19  |  Submit date:2020/04/07
bioinformatics  computational biology  gene ontology  protein  pathways  type 2 diabetes  neurological disease  
Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 期号: 1, 页码: 1665
Authors:  Gao, Lei;  Hu, Yong;  Tian, Yahui;  Fan, Zhenzhen;  Wang, Kun;  Li, Hongdan;  Zhou, Qian;  Zeng, Guandi;  Hu, Xin;  Yu, Lei;  Zhou, Shiyu;  Tong, Xinyuan;  Huang, Hsinyi;  Chen, Haiquan;  Liu, Qingsong;  Liu, Wanting;  Zhang, Gong;  Zeng, Musheng;  Zhou, Guangbiao;  He, Qingyu;  Ji, Hongbin;  Chen, Liang
View  |  Adobe PDF(2284Kb)  |  Favorite  |  View/Download:108/14  |  Submit date:2019/07/12
GATA4  
The Applications of Radiomics in Precision Diagnosis and Treatment of Oncology: Opportunities and Challenges 期刊论文
Theranostics, 2019, 卷号: 9, 期号: 5, 页码: 1303-1322
Authors:  Liu, Zhenyu;  Wang, Shuo;  Dong, Di;  Wei, Jingwei;  Fang, Cheng;  Zhou, Xuezhi;  Sun, Kai;  Li, Longfei;  Li, Bo;  Wang, Meiyun;  Tian, Jie
View  |  Adobe PDF(2057Kb)  |  Favorite  |  View/Download:144/26  |  Submit date:2019/04/30
Radiomics  Medical Imaging  Precision Diagnosis And Treatment  Oncology  
p53-dependent upregulation of miR-16-2 by sanguinarine induces cell cycle arrest and apoptosis in hepatocellular carcinoma 期刊论文
CANCER LETTERS, 2019, 卷号: 459, 页码: 50-58
Authors:  Zhang, Beilei;  Wang, Xinan;  Deng, Jiacong;  Zheng, Haifeng;  Liu, Wei;  Chen, Si;  Tian, Jie;  Wang, Fu
Favorite  |  View/Download:45/0  |  Submit date:2019/12/16
miRNA-16  p53  Sanguinarine  Cell cycle  Apoptosis  
MRI features can predict EGFR expression in lower grade gliomas: A voxel-based radiomic analysis 期刊论文
EUROPEAN RADIOLOGY, 2018, 卷号: 28, 期号: 1, 页码: 356-362
Authors:  Li, Yiming;  Liu, Xing;  Xu, Kaibin;  Qian, Zenghui;  Wang, Kai;  Fan, Xing;  Li, Shaowu;  Wang, Yinyan;  Jiang, Tao
Favorite  |  View/Download:72/0  |  Submit date:2018/10/10
Radiomics  Lower Grade Glioma  Egfr  Mri  Prediction  
MRI features predict p53 status in lower-grade gliomas via a machine-learning approach 期刊论文
NEUROIMAGE-CLINICAL, 2018, 卷号: 17, 页码: 306-311
Authors:  Li, Yiming;  Qian, Zenghui;  Xu, Kaibin;  Wang, Kai;  Fan, Xing;  Li, Shaowu;  Jiang, Tao;  Liu, Xing;  Wang, Yinyan
Favorite  |  View/Download:71/0  |  Submit date:2018/10/10
P53  Lower-grade Gliomas  Radiogenomics  Prediction  Machine Learning  
Systematic synergy modeling: understanding drug synergy from a systems biology perspective 期刊论文
BMC SYSTEMS BIOLOGY, 2015, 卷号: 9, 期号: 2015, 页码: 56
Authors:  Chen, Di;  Liu, Xi;  Yang, Yiping;  Yang, Hongjun;  Lu, Peng;  Lu,Peng
View  |  Adobe PDF(1011Kb)  |  Favorite  |  View/Download:190/8  |  Submit date:2015/11/04
Drug Synergy  Systematic Modeling  
Comprehensive Evaluation of the Anti-Angiogenic and Anti-Neoplastic Effects of Endostar on Liver Cancer through Optical Molecular Imaging 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 1, 页码: -
Authors:  Zhang, Qian;  Du, Yang;  Xue, Zhenwen;  Chi, Chongwei;  Jia, Xiaohua;  Tian, Jie
View  |  Adobe PDF(9977Kb)  |  Favorite  |  View/Download:185/20  |  Submit date:2015/08/12