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An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography 期刊论文
BMC BIOLOGY, 2023, 卷号: 21, 期号: 1, 页码: 14
作者:  Chang, Sheng;  Li, Linlin;  Hong, Bei;  Liu, Jing;  Xu, Yuxuan;  Pang, Keliang;  Zhang, Lina;  Han, Hua;  Chen, Xi
收藏  |  浏览/下载：59/0  |  提交时间：2023/11/16
Serial section electron tomography  3D EM  Semi-auto locating  Auto-alignment  Missing-information restoration  Semi-auto segmentation  Workflow  Synapse  
A novel registration method for long-serial section images of EM with a serial split technique based on unsupervised optical flow network 期刊论文
BIOINFORMATICS, 2023, 卷号: 39, 期号: 8, 页码: 11
作者:  Xin, Tong;  Lv, Yanan;  Chen, Haoran;  Li, Linlin;  Shen, Lijun;  Shan, Guangcun;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载：75/0  |  提交时间：2023/11/17
City 5.0: Towards Spatial Symbiotic Intelligence via DAOs and Parallel Systems 期刊论文
IEEE TRANSACTIONS ON INTELLIGENT VEHICLES, 2023, 卷号: 8, 期号: 7, 页码: 3767-3770
作者:  Lin, Yilun;  Hu, Wei;  Chen, Xi;  Li, Shuang;  Wang, Fei-Yue
收藏  |  浏览/下载：57/0  |  提交时间：2023/11/17
City 5.0  DAOs  Parallel System  Spatial Symbiotic Intelligence  
Joint reconstruction of neuron and ultrastructure via connectivity consensus in electron microscope volumes 期刊论文
BMC Bioinformatics, 2022, 卷号: 23, 期号: 1, 页码: 23
作者:  Hong,Bei;  Liu,Jing;  Zhai,Hao;  Liu,Jiazheng;  Shen,Lijun;  Chen,Xi;  Xie,Qiwei;  Han,Hua
Adobe PDF(3091Kb)  |  收藏  |  浏览/下载：262/73  |  提交时间：2022/11/14
Connectomics  Reconstruction  Connectivity concept  Joint optimization  Electron microscope volumes  
Fusion and expansion of vitellogenin vesicles during Caenorhabditis elegans intestinal senescence 期刊论文
AGING CELL, 2022, 页码: 13
作者:  Zhai, Chao;  Zhang, Nan;  Li, Xi-Xia;  Chen, Xi;  Sun, Fei;  Dong, Meng-Qiu
收藏  |  浏览/下载：154/0  |  提交时间：2022/11/14
Aging  C  elegans  Senescence  Vesicle fusion  Vitellogenin  Yolk  
Expected affine: A registration method for damaged section in serial sections electron microscopy 期刊论文
FRONTIERS IN NEUROINFORMATICS, 2022, 卷号: 16, 页码: 11
作者:  Xin, Tong;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载：170/0  |  提交时间：2022/11/14
image registration  SSEM  broken sections  section fold  section crack  
Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data 期刊论文
CELL REPORTS, 2022, 卷号: 40, 期号: 5, 页码: 28
作者:  Liu, Jing;  Qi, Junqian;  Chen, Xi;  Li, Zhenchen;  Hong, Bei;  Ma, Hongtu;  Li, Guoqing;  Shen, Lijun;  Liu, Danqian;  Kong, Yu;  Zhai, Hao;  Xie, Qiwei;  Han, Hua;  Yang, Yang
收藏  |  浏览/下载：231/0  |  提交时间：2022/09/19
Denoising of scanning electron microscope images for biological ultrastructure enhancement 期刊论文
JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 2022, 卷号: 20, 期号: 03, 页码: 21
作者:  Chang, Sheng;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
Adobe PDF(4726Kb)  |  收藏  |  浏览/下载：237/33  |  提交时间：2022/09/19
SEM  noise model  denoising  variance stabilization transformation  two-stage multi-loss  deep learning  
Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy 期刊论文
Journal of Molecular Cell Biology, 2022, 页码: 已录用
作者:  Yi Jiang;  Linlin Li;  Keliang Pang;  Jiazheng Liu;  Bohao Chen;  Jingbin Yuan;  Lijun Shen;  Xi Chen;  Bai Lu;  Hua Han
Adobe PDF(689Kb)  |  收藏  |  浏览/下载：348/155  |  提交时间：2022/07/01
An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments 期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:  Pang, Keliang;  Jiang, Richeng;  Zhang, Wei;  Yang, Zhengyi;  Li, Lin-Lin;  Shimozawa, Makoto;  Tambaro, Simone;  Mayer, Johanna;  Zhang, Baogui;  Li, Man;  Wang, Jiesi;  Liu, Hang;  Yang, Ailing;  Chen, Xi;  Liu, Jiazheng;  Winblad, Bengt;  Han, Hua;  Jiang, Tianzi;  Wang, Weiwen;  Nilsson, Per;  Guo, Wei;  Lu, Bai
收藏  |  浏览/下载：199/0  |  提交时间：2021/12/28