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An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography 期刊论文
BMC BIOLOGY, 2023, 卷号: 21, 期号: 1, 页码: 14
作者:  Chang, Sheng;  Li, Linlin;  Hong, Bei;  Liu, Jing;  Xu, Yuxuan;  Pang, Keliang;  Zhang, Lina;  Han, Hua;  Chen, Xi
收藏  |  浏览/下载：63/0  |  提交时间：2023/11/16
Serial section electron tomography  3D EM  Semi-auto locating  Auto-alignment  Missing-information restoration  Semi-auto segmentation  Workflow  Synapse  
A novel registration method for long-serial section images of EM with a serial split technique based on unsupervised optical flow network 期刊论文
BIOINFORMATICS, 2023, 卷号: 39, 期号: 8, 页码: 11
作者:  Xin, Tong;  Lv, Yanan;  Chen, Haoran;  Li, Linlin;  Shen, Lijun;  Shan, Guangcun;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载：76/0  |  提交时间：2023/11/17
Joint reconstruction of neuron and ultrastructure via connectivity consensus in electron microscope volumes 期刊论文
BMC Bioinformatics, 2022, 卷号: 23, 期号: 1, 页码: 23
作者:  Hong,Bei;  Liu,Jing;  Zhai,Hao;  Liu,Jiazheng;  Shen,Lijun;  Chen,Xi;  Xie,Qiwei;  Han,Hua
Adobe PDF(3091Kb)  |  收藏  |  浏览/下载：264/73  |  提交时间：2022/11/14
Connectomics  Reconstruction  Connectivity concept  Joint optimization  Electron microscope volumes  
Expected affine: A registration method for damaged section in serial sections electron microscopy 期刊论文
FRONTIERS IN NEUROINFORMATICS, 2022, 卷号: 16, 页码: 11
作者:  Xin, Tong;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载：171/0  |  提交时间：2022/11/14
image registration  SSEM  broken sections  section fold  section crack  
Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data 期刊论文
CELL REPORTS, 2022, 卷号: 40, 期号: 5, 页码: 28
作者:  Liu, Jing;  Qi, Junqian;  Chen, Xi;  Li, Zhenchen;  Hong, Bei;  Ma, Hongtu;  Li, Guoqing;  Shen, Lijun;  Liu, Danqian;  Kong, Yu;  Zhai, Hao;  Xie, Qiwei;  Han, Hua;  Yang, Yang
收藏  |  浏览/下载：233/0  |  提交时间：2022/09/19
Denoising of scanning electron microscope images for biological ultrastructure enhancement 期刊论文
JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 2022, 卷号: 20, 期号: 03, 页码: 21
作者:  Chang, Sheng;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
Adobe PDF(4726Kb)  |  收藏  |  浏览/下载：239/33  |  提交时间：2022/09/19
SEM  noise model  denoising  variance stabilization transformation  two-stage multi-loss  deep learning  
Performance Analysis in Serial-section Electron Microscopy Image Registration of Neuronal Tissue 会议论文
, 美国圣地亚哥, 2022-1
作者:  Chen BH(陈波昊);  Xin T(辛桐);  Han H(韩华);  Chen X(陈曦)
Adobe PDF(1634Kb)  |  收藏  |  浏览/下载：212/52  |  提交时间：2022/06/14
Registration accuracy  Serial section  Neuronal structure  Spherical deformation model  
Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy 期刊论文
Journal of Molecular Cell Biology, 2022, 页码: 已录用
作者:  Yi Jiang;  Linlin Li;  Keliang Pang;  Jiazheng Liu;  Bohao Chen;  Jingbin Yuan;  Lijun Shen;  Xi Chen;  Bai Lu;  Hua Han
Adobe PDF(689Kb)  |  收藏  |  浏览/下载：349/155  |  提交时间：2022/07/01
An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments 期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:  Pang, Keliang;  Jiang, Richeng;  Zhang, Wei;  Yang, Zhengyi;  Li, Lin-Lin;  Shimozawa, Makoto;  Tambaro, Simone;  Mayer, Johanna;  Zhang, Baogui;  Li, Man;  Wang, Jiesi;  Liu, Hang;  Yang, Ailing;  Chen, Xi;  Liu, Jiazheng;  Winblad, Bengt;  Han, Hua;  Jiang, Tianzi;  Wang, Weiwen;  Nilsson, Per;  Guo, Wei;  Lu, Bai
收藏  |  浏览/下载：200/0  |  提交时间：2021/12/28
UTR: UNSUPERVISED LEARNING OF THICKNESS-INSENSITIVE REPRESENTATIONS FOR ELECTRON MICROSCOPE IMAGE 会议论文
, 美国阿拉斯加, 2021-10
作者:  Xin T(辛桐);  Chen BH(陈波昊);  Chen X(陈曦);  Han H(韩华)
Adobe PDF(2365Kb)  |  收藏  |  浏览/下载：193/35  |  提交时间：2022/06/14
Feature Descriptor  Unsupervised learning  Electron Microscopy  Image registration  FIB-SEM