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An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography 期刊论文
BMC BIOLOGY, 2023, 卷号: 21, 期号: 1, 页码: 14
作者:  Chang, Sheng;  Li, Linlin;  Hong, Bei;  Liu, Jing;  Xu, Yuxuan;  Pang, Keliang;  Zhang, Lina;  Han, Hua;  Chen, Xi
收藏  |  浏览/下载:63/0  |  提交时间:2023/11/16
Serial section electron tomography  3D EM  Semi-auto locating  Auto-alignment  Missing-information restoration  Semi-auto segmentation  Workflow  Synapse  
A novel registration method for long-serial section images of EM with a serial split technique based on unsupervised optical flow network 期刊论文
BIOINFORMATICS, 2023, 卷号: 39, 期号: 8, 页码: 11
作者:  Xin, Tong;  Lv, Yanan;  Chen, Haoran;  Li, Linlin;  Shen, Lijun;  Shan, Guangcun;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载:76/0  |  提交时间:2023/11/17
Joint reconstruction of neuron and ultrastructure via connectivity consensus in electron microscope volumes 期刊论文
BMC Bioinformatics, 2022, 卷号: 23, 期号: 1, 页码: 23
作者:  Hong,Bei;  Liu,Jing;  Zhai,Hao;  Liu,Jiazheng;  Shen,Lijun;  Chen,Xi;  Xie,Qiwei;  Han,Hua
Adobe PDF(3091Kb)  |  收藏  |  浏览/下载:264/73  |  提交时间:2022/11/14
Connectomics  Reconstruction  Connectivity concept  Joint optimization  Electron microscope volumes  
Expected affine: A registration method for damaged section in serial sections electron microscopy 期刊论文
FRONTIERS IN NEUROINFORMATICS, 2022, 卷号: 16, 页码: 11
作者:  Xin, Tong;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载:171/0  |  提交时间:2022/11/14
image registration  SSEM  broken sections  section fold  section crack  
Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data 期刊论文
CELL REPORTS, 2022, 卷号: 40, 期号: 5, 页码: 28
作者:  Liu, Jing;  Qi, Junqian;  Chen, Xi;  Li, Zhenchen;  Hong, Bei;  Ma, Hongtu;  Li, Guoqing;  Shen, Lijun;  Liu, Danqian;  Kong, Yu;  Zhai, Hao;  Xie, Qiwei;  Han, Hua;  Yang, Yang
收藏  |  浏览/下载:233/0  |  提交时间:2022/09/19
Denoising of scanning electron microscope images for biological ultrastructure enhancement 期刊论文
JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 2022, 卷号: 20, 期号: 03, 页码: 21
作者:  Chang, Sheng;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
Adobe PDF(4726Kb)  |  收藏  |  浏览/下载:239/33  |  提交时间:2022/09/19
SEM  noise model  denoising  variance stabilization transformation  two-stage multi-loss  deep learning  
Performance Analysis in Serial-section Electron Microscopy Image Registration of Neuronal Tissue 会议论文
, 美国圣地亚哥, 2022-1
作者:  Chen BH(陈波昊);  Xin T(辛桐);  Han H(韩华);  Chen X(陈曦)
Adobe PDF(1634Kb)  |  收藏  |  浏览/下载:212/52  |  提交时间:2022/06/14
Registration accuracy  Serial section  Neuronal structure  Spherical deformation model  
Deep residual contextual and subpixel convolution network for automated neuronal structure segmentation in micro-connectomics 期刊论文
Computer Methods and Programs in Biomedicine, 2022, 卷号: 219, 页码: 106759
作者:  Xiao, Chi;  Hong, Bei;  Liu, Jing;  Tang, Yuanyan;  Xie, Qiwei;  Han, Hua
Adobe PDF(2731Kb)  |  收藏  |  浏览/下载:184/50  |  提交时间:2023/01/12
Deep learning  Neuronal structure segmentation  Subpixel convolution  Electron microscopy  Micro-Connectomics  
Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy 期刊论文
Journal of Molecular Cell Biology, 2022, 页码: 已录用
作者:  Yi Jiang;  Linlin Li;  Keliang Pang;  Jiazheng Liu;  Bohao Chen;  Jingbin Yuan;  Lijun Shen;  Xi Chen;  Bai Lu;  Hua Han
Adobe PDF(689Kb)  |  收藏  |  浏览/下载:349/155  |  提交时间:2022/07/01
Aligned Organization of Synapses and Mitochondria in Auditory Hair Cells 期刊论文
NEUROSCIENCE BULLETIN, 2021, 页码: 14
作者:  Liu, Jing;  Wang, Shengxiong;  Lu, Yan;  Wang, Haoyu;  Wang, Fangfang;  Qiu, Miaoxin;  Xie, Qiwei;  Han, Hua;  Hua, Yunfeng
收藏  |  浏览/下载:204/0  |  提交时间:2021/12/28
Inner hair cell  Ribbon synapse  Mitochondrial network  Volume electron microscopy  AI-based image processing