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基于影像基因组学的脑结构与精神健康的关联机制研究 学位论文
, 2024
Authors:  胡珂
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精神健康  脑结构  影像基因组学  全基因组关联分析  因果关系  
Deciphering the neural mechanisms of miR-134 in major depressive disorder with population-based and person-specific imaging transcriptomic techniques 期刊论文
PSYCHIATRY RESEARCH, 2023, 卷号: 329, 页码: 12
Authors:  Lou, Jing;  Liu, Kai;  Wen, Junyan;  He, Yini;  Sun, Yuqing;  Tian, Xiaohan;  Hu, Ke;  Deng, Yanjia;  Liu, Bing;  Wen, Ge
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Major depressive disorder (MDD)  miR-134  Two -stage cross -scale imaging transcriptomic  analyses  Biomarkers  Multi-omics  
Distinct spatiotemporal subtypes of amyloid deposition are associated with diverging disease profiles in cognitively normal and mild cognitive impairment individuals 期刊论文
TRANSLATIONAL PSYCHIATRY, 2023, 卷号: 13, 期号: 1, 页码: 35
Authors:  Sun, Yuqing;  Zhao, Yuxin;  Hu, Ke;  Wang, Meng;  Liu, Yong;  Liu, Bing
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The development of cortical functional hierarchy is associated with the molecular organization of prenatal/postnatal periods 期刊论文
CEREBRAL CORTEX, 2022, 页码: 14
Authors:  Zhao, Yuxin;  Wang, Meng;  Hu, Ke;  Wang, Qi;  Lou, Jing;  Fan, Lingzhong;  Liu, Bing
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cortical development  fMRI  gene expression  postnatal  prenatal  
A Pathway-Specific Polygenic Risk Score Is Associated with Tau Pathology and Cognitive Decline 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2022, 卷号: 85, 期号: 4, 页码: 1745-1754
Authors:  Sun, Yuqing;  Wang, Meng;  Zhao, Yuxin;  Hu, Ke;  Liu, Yong;  Liu, Bing
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Alzheimer's disease  cognitive function genetic risk scores  pathway  tau  
Predicting Treatment Response in Schizophrenia With Magnetic Resonance Imaging and Polygenic Risk Score 期刊论文
FRONTIERS IN GENETICS, 2022, 卷号: 13, 页码: 11
Authors:  Wang, Meng;  Hu, Ke;  Fan, Lingzhong;  Yan, Hao;  Li, Peng;  Jiang, Tianzi;  Liu, Bing
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schizophrenia  treatment prediction  XGBoost  polygenic risk score  magnetic resonance imaging  
Dynamic reconfiguration of human brain networks across altered states of consciousness 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2022, 卷号: 419, 页码: 11
Authors:  Liu, Haiyang;  Hu, Ke;  Peng, Yingjie;  Tian, Xiaohan;  Wang, Meng;  Ma, Bo;  Wu, Youxuan;  Sun, Wanchen;  Liu, Bing;  Li, Ang;  Han, Ruquan
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Functional magnetic resonance imaging  Multilayer networks  Dynamic functional connectivity  Consciousness  Sedation  Dexmedetomidine  
Multisite schizophrenia classification by integrating structural magnetic resonance imaging data with polygenic risk score 期刊论文
NEUROIMAGE-CLINICAL, 2021, 卷号: 32, 页码: 9
Authors:  Hu, Ke;  Wang, Meng;  Liu, Yong;  Yan, Hao;  Song, Ming;  Chen, Jun;  Chen, Yunchun;  Wang, Huaning;  Guo, Hua;  Wan, Ping;  Lv, Luxian;  Yang, Yongfeng;  Li, Peng;  Lu, Lin;  Yan, Jun;  Wang, Huiling;  Zhang, Hongxing;  Zhang, Dai;  Wu, Huawang;  Ning, Yuping;  Jiang, Tianzi;  Liu, Bing
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Schizophrenia  Classification  Structural magnetic resonance imaging  Gray matter volume  Polygenic risk score  Machine learning  
Predicting brain age during typical and atypical development based on structural and functional neuroimaging 期刊论文
Authors:  Wang, Qi;  Hu, Ke;  Wang, Meng;  Zhao, Yuxin;  Liu, Yong;  Fan, Lingzhong;  Liu, Bing
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autism spectrum disorder  autism spectrum disorder  brain age prediction  brain age prediction  developmental heterogeneity  developmental heterogeneity  multimodal magnetic resonance imaging  multimodal magnetic resonance imaging  predictor weights analysis  predictor weights analysis