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基于影像基因组学的脑结构与精神健康的关联机制研究 学位论文
, 2024
Authors:  胡珂
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精神健康  脑结构  影像基因组学  全基因组关联分析  因果关系  
Deciphering the neural mechanisms of miR-134 in major depressive disorder with population-based and person-specific imaging transcriptomic techniques 期刊论文
PSYCHIATRY RESEARCH, 2023, 卷号: 329, 页码: 12
Authors:  Lou, Jing;  Liu, Kai;  Wen, Junyan;  He, Yini;  Sun, Yuqing;  Tian, Xiaohan;  Hu, Ke;  Deng, Yanjia;  Liu, Bing;  Wen, Ge
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Major depressive disorder (MDD)  miR-134  Two -stage cross -scale imaging transcriptomic  analyses  Biomarkers  Multi-omics  
Distinct spatiotemporal subtypes of amyloid deposition are associated with diverging disease profiles in cognitively normal and mild cognitive impairment individuals 期刊论文
TRANSLATIONAL PSYCHIATRY, 2023, 卷号: 13, 期号: 1, 页码: 35
Authors:  Sun, Yuqing;  Zhao, Yuxin;  Hu, Ke;  Wang, Meng;  Liu, Yong;  Liu, Bing
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The development of cortical functional hierarchy is associated with the molecular organization of prenatal/postnatal periods 期刊论文
CEREBRAL CORTEX, 2022, 页码: 14
Authors:  Zhao, Yuxin;  Wang, Meng;  Hu, Ke;  Wang, Qi;  Lou, Jing;  Fan, Lingzhong;  Liu, Bing
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cortical development  fMRI  gene expression  postnatal  prenatal  
A Pathway-Specific Polygenic Risk Score Is Associated with Tau Pathology and Cognitive Decline 期刊论文
JOURNAL OF ALZHEIMERS DISEASE, 2022, 卷号: 85, 期号: 4, 页码: 1745-1754
Authors:  Sun, Yuqing;  Wang, Meng;  Zhao, Yuxin;  Hu, Ke;  Liu, Yong;  Liu, Bing
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Alzheimer's disease  cognitive function genetic risk scores  pathway  tau  
Predicting Treatment Response in Schizophrenia With Magnetic Resonance Imaging and Polygenic Risk Score 期刊论文
FRONTIERS IN GENETICS, 2022, 卷号: 13, 页码: 11
Authors:  Wang, Meng;  Hu, Ke;  Fan, Lingzhong;  Yan, Hao;  Li, Peng;  Jiang, Tianzi;  Liu, Bing
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schizophrenia  treatment prediction  XGBoost  polygenic risk score  magnetic resonance imaging  
Dynamic reconfiguration of human brain networks across altered states of consciousness 期刊论文
BEHAVIOURAL BRAIN RESEARCH, 2022, 卷号: 419, 页码: 11
Authors:  Liu, Haiyang;  Hu, Ke;  Peng, Yingjie;  Tian, Xiaohan;  Wang, Meng;  Ma, Bo;  Wu, Youxuan;  Sun, Wanchen;  Liu, Bing;  Li, Ang;  Han, Ruquan
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Functional magnetic resonance imaging  Multilayer networks  Dynamic functional connectivity  Consciousness  Sedation  Dexmedetomidine  
Multisite schizophrenia classification by integrating structural magnetic resonance imaging data with polygenic risk score 期刊论文
NEUROIMAGE-CLINICAL, 2021, 卷号: 32, 页码: 9
Authors:  Hu, Ke;  Wang, Meng;  Liu, Yong;  Yan, Hao;  Song, Ming;  Chen, Jun;  Chen, Yunchun;  Wang, Huaning;  Guo, Hua;  Wan, Ping;  Lv, Luxian;  Yang, Yongfeng;  Li, Peng;  Lu, Lin;  Yan, Jun;  Wang, Huiling;  Zhang, Hongxing;  Zhang, Dai;  Wu, Huawang;  Ning, Yuping;  Jiang, Tianzi;  Liu, Bing
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Schizophrenia  Classification  Structural magnetic resonance imaging  Gray matter volume  Polygenic risk score  Machine learning  
Predicting brain age during typical and atypical development based on structural and functional neuroimaging 期刊论文
HUMAN BRAIN MAPPING, 2021, 页码: 13
Authors:  Wang, Qi;  Hu, Ke;  Wang, Meng;  Zhao, Yuxin;  Liu, Yong;  Fan, Lingzhong;  Liu, Bing
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autism spectrum disorder  autism spectrum disorder  brain age prediction  brain age prediction  developmental heterogeneity  developmental heterogeneity  multimodal magnetic resonance imaging  multimodal magnetic resonance imaging  predictor weights analysis  predictor weights analysis