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Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors 期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
Authors:  Zhang,Pei;  Du,Yang;  Bai,Hua;  Wang,Zhijie;  Duan,Jianchun;  Wang,Xin;  Zhong,Jia;  Wan,Rui;  Xu,Jiachen;  He,Xiran;  Wang,Di;  Fei,Kailun;  Yu,Ruofei;  Tian,Jie;  Wang,Jie
Favorite  |  View/Download:232/0  |  Submit date:2022/11/21
Tucidinostat  Tumor microenvironment  PD-L1  CCL5  Solid tumor  
Peptidic microarchitecture-trapped tumor vaccine combined with immune checkpoint inhibitor or PI3K gamma inhibitor can enhance immunogenicity and eradicate tumors 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 卷号: 10, 期号: 2, 页码: 13
Authors:  Du, Yang;  Liu, Ye;  Wang, Di;  Bai, Hua;  Wang, Zhijie;  He, Xiran;  Zhang, Pei;  Tian, Jie;  Wang, Jie
Favorite  |  View/Download:248/0  |  Submit date:2022/06/06
immunotherapy  immunogenicity  vaccine  tumor microenvironment  lymphocytes  tumor infiltrating  macrophages  
ImmunoAIzer: A Deep Learning-Based Computational Framework to Characterize Cell Distribution and Gene Mutation in Tumor Microenvironment 期刊论文
CANCERS, 2021, 卷号: 13, 期号: 7, 页码: 21
Authors:  Bian, Chang;  Wang, Yu;  Lu, Zhihao;  An, Yu;  Wang, Hanfan;  Kong, Lingxin;  Du, Yang;  Tian, Jie
Adobe PDF(14076Kb)  |  Favorite  |  View/Download:315/27  |  Submit date:2021/05/17
deep learning  cell distribution  biomarker  tumor gene mutation  tumor microenvironment (TME)  semi-supervised learning  hematoxylin and eosin (H&  E)  
Predicting response to immunotherapy in advanced non-small-cell lung cancer using tumor mutational burden radiomic biomarker 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 卷号: 8, 期号: 2, 页码: 10
Authors:  He, Bingxi;  Dong, Di;  She, Yunlang;  Zhou, Caicun;  Fang, Mengjie;  Zhu, Yongbei;  Zhang, Henghui;  Huang, Zhipei;  Jiang, Tao;  Tian, Jie;  Chen, Chang
View  |  Adobe PDF(5232Kb)  |  Favorite  |  View/Download:375/61  |  Submit date:2020/08/24
immunotherapy  lung neoplasms  tumor microenvironment  biomarkers  tumor  biostatistics  
Hypoxia-active nanoparticles used in tumor theranostic 期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2019, 卷号: 14, 页码: 3705-3722
Authors:  Wang, Yaqin;  Shang, Wenting;  Niu, Meng;  Tian, Jie;  Xu, Ke
Favorite  |  View/Download:338/0  |  Submit date:2019/07/11
prodrug  tumor microenvironment  metal complex  bioreductive