CASIA OpenIR  > 中国科学院分子影像重点实验室
A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation
Tianming Song; Xia Liu; Yawei Qu; Haixiao Liu; Chengpeng Bao; Chengcai Leng; Zhenhua Hu; Kun Wang; Jie Tian
Source PublicationMolecular Imaging
2015-08
Volume14Issue:8Pages:7290
AbstractCerenkov luminescence imaging is an emerging optical technique for imaging the distribution of radiopharmaceuticals in vivo. However,
because of the light scattering effect, it cannot obtain optical information from deep internal organs. To overcome this challenge, we
established a novel endoscopic Cerenkov luminescence imaging system that used a clinically approved laparoscope and an electronmultiplying charge-coupled device camera. We assessed the performance of the system through a series of in vitro and in vivo experiments. The results demonstrated superior superficial imaging resolution (0.1 mm), a large field of view (500 mm2 with 10 mm imaging
distance), and superb imaging sensitivity (imaging 1 μCi) of our system. It captured the weak Cerenkov signal from internal organs
successfully and was applied to intraoperative surgical navigation of tumor resection. It offered objective information of the tumor location
and tumor residual during the surgical operation. This technique holds great potential for clinical translation.
KeywordEndoscopic Cerenkov Luminescence Imaging System
WOS IDWOS:000365597500002
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Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/11997
Collection中国科学院分子影像重点实验室
Corresponding AuthorZhenhua Hu
Recommended Citation
GB/T 7714
Tianming Song,Xia Liu,Yawei Qu,et al. A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation[J]. Molecular Imaging,2015,14(8):7290.
APA Tianming Song.,Xia Liu.,Yawei Qu.,Haixiao Liu.,Chengpeng Bao.,...&Jie Tian.(2015).A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation.Molecular Imaging,14(8),7290.
MLA Tianming Song,et al."A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation".Molecular Imaging 14.8(2015):7290.
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