CASIA OpenIR  > 中国科学院分子影像重点实验室
A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation
Tianming Song; Xia Liu; Yawei Qu; Haixiao Liu; Chengpeng Bao; Chengcai Leng; Zhenhua Hu; Kun Wang; Jie Tian
2015-08
发表期刊Molecular Imaging
卷号14期号:8页码:7290
摘要Cerenkov luminescence imaging is an emerging optical technique for imaging the distribution of radiopharmaceuticals in vivo. However,
because of the light scattering effect, it cannot obtain optical information from deep internal organs. To overcome this challenge, we
established a novel endoscopic Cerenkov luminescence imaging system that used a clinically approved laparoscope and an electronmultiplying charge-coupled device camera. We assessed the performance of the system through a series of in vitro and in vivo experiments. The results demonstrated superior superficial imaging resolution (0.1 mm), a large field of view (500 mm2 with 10 mm imaging
distance), and superb imaging sensitivity (imaging 1 μCi) of our system. It captured the weak Cerenkov signal from internal organs
successfully and was applied to intraoperative surgical navigation of tumor resection. It offered objective information of the tumor location
and tumor residual during the surgical operation. This technique holds great potential for clinical translation.
关键词Endoscopic Cerenkov Luminescence Imaging System
WOS记录号WOS:000365597500002
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被引频次:6[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/11997
专题中国科学院分子影像重点实验室
通讯作者Zhenhua Hu
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GB/T 7714
Tianming Song,Xia Liu,Yawei Qu,et al. A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation[J]. Molecular Imaging,2015,14(8):7290.
APA Tianming Song.,Xia Liu.,Yawei Qu.,Haixiao Liu.,Chengpeng Bao.,...&Jie Tian.(2015).A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation.Molecular Imaging,14(8),7290.
MLA Tianming Song,et al."A Novel Endoscopic Cerenkov Luminescence Imaging System for Intraoperative Surgical Navigation".Molecular Imaging 14.8(2015):7290.
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