Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction

doi:10.1364/BOE.7.002342

	Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction
	Jiang, Shixin 1; Liu, Jie1 ; An, Yu 1; Zhang, Guanglei 1; Ye, Jinzuo2 ; Mao, Yamin2 ; He, Kunshan2 ; Chi, Chongwei2,3 ; Tian, Jie 2,3
发表期刊	BIOMEDICAL OPTICS EXPRESS
	2016-06-01
卷号	7 期号:6 页码:2342-2359
文章类型	Article
摘要	Fluorescence molecular tomography (FMT) is a promising tomographic method in preclinical research, which enables noninvasive real-time three-dimensional (3-D) visualization for in vivo studies. The ill-posedness of the FMT reconstruction problem is one of the many challenges in the studies of FMT. In this paper, we propose a l(2,1)-norm optimization method using a priori information, mainly the structured sparsity of the fluorescent regions for FMT reconstruction. Compared to standard sparsity methods, the structured sparsity methods are often superior in reconstruction accuracy since the structured sparsity utilizes correlations or structures of the reconstructed image. To solve the problem effectively, the Nesterov's method was used to accelerate the computation. To evaluate the performance of the proposed l(2,1)-norm method, numerical phantom experiments and in vivo mouse experiments are conducted. The results show that the proposed method not only achieves accurate and desirable fluorescent source reconstruction, but also demonstrates enhanced robustness to noise. (C) 2016 Optical Society of America
关键词	Image Reconstruction Techniques Spectroscopy Fluorescence And Luminescence Tomography
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
DOI	10.1364/BOE.7.002342
关键词[WOS]	DIFFUSE OPTICAL TOMOGRAPHY ; ELEMENT BASED TOMOGRAPHY ; IMAGE-RECONSTRUCTION ; BIOLUMINESCENCE TOMOGRAPHY ; SPARSITY REGULARIZATION ; ALGORITHM ; LIGHT ; INFORMATION ; MICROSCOPY ; TISSUE
收录类别	SCI
语种	英语
项目资助者	National Natural Science Foundation of China(81571836 ; Fundamental Research Funds for the Central Universities(2015JBM026) ; China Postdoctoral Science Foundation(2015M570032 ; Beijing Natural Science Foundation(7164270 ; Open Research Project from SKLMCCS(20150103) ; 81227901 ; 2015T80155) ; 20140491524) ; 61231004 ; 61501462)
WOS研究方向	Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000377514000023
引用统计	被引频次：38[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/12187
专题	中国科学院分子影像重点实验室
通讯作者	Liu, Jie
作者单位	1.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Dept Biomed Engn, 3 Shangyuancun, Beijing 100044, Peoples R China 2.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing Key Lab Mol Imaging, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Jiang, Shixin,Liu, Jie,An, Yu,et al. Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction[J]. BIOMEDICAL OPTICS EXPRESS,2016,7(6):2342-2359.
APA	Jiang, Shixin.,Liu, Jie.,An, Yu.,Zhang, Guanglei.,Ye, Jinzuo.,...&Tian, Jie.(2016).Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction.BIOMEDICAL OPTICS EXPRESS,7(6),2342-2359.
MLA	Jiang, Shixin,et al."Novel l(2,1)-norm optimization method for fluorescence molecular tomography reconstruction".BIOMEDICAL OPTICS EXPRESS 7.6(2016):2342-2359.

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