Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
In vivo pentamodal tomographic imaging for small animals | |
Liu, Muhan1,2,3; Guo, Hongbo3,4; Liu, Hongbo1,2,3; Zhang, Zeyu3; Chi, Chongwei3; Hui, Hui3; Dong, Di3; Hu, Zhenhua3,5; Tian, Jie1,2,3,5 | |
发表期刊 | BIOMEDICAL OPTICS EXPRESS |
2017-03-01 | |
卷号 | 8期号:3页码:1356-1371 |
文章类型 | Article |
摘要 | Multimodality molecular imaging emerges as a powerful strategy for correlating multimodal information. We developed a pentamodal imaging system which can perform positron emission tomography, bioluminescence tomography, fluorescence molecular tomography, Cerenkov luminescence tomography and X-ray computed tomography successively. Performance of sub-systems corresponding to different modalities were characterized. In vivo multimodal imaging of an orthotopic hepatocellular carcinoma xenograft mouse model was performed, and acquired multimodal images were fused. The feasibility of pentamodal tomographic imaging system was successfully validated with the imaging application on the mouse model. The ability of integrating anatomical, metabolic, and pharmacokinetic information promises applications of multimodality molecular imaging in precise medicine. (C) 2017 Optical Society of America. |
关键词 | Pentamodal Tomographic Imaging |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences |
DOI | 10.1364/BOE.8.001356 |
关键词[WOS] | BIOLUMINESCENCE TOMOGRAPHY ; CLINICAL-APPLICATIONS ; MRI ; DEVICES ; SYSTEM ; RECONSTRUCTION ; MODALITIES ; ALGORITHM ; SPECT/CT ; PLATFORM |
收录类别 | SCI |
语种 | 英语 |
项目资助者 | National Natural Science Foundation of China (NSFC)(81227901 ; National Key Research and Development Program of China(2016YFC0102600) ; 81527805 ; 61231004 ; 61622117 ; 81671759) |
WOS研究方向 | Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
WOS类目 | Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
WOS记录号 | WOS:000395942600007 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/14427 |
专题 | 中国科学院分子影像重点实验室 |
作者单位 | 1.Xidian Univ, Engn Res Ctr Mol & Neuro Imaging, Minist Educ, Xian 710071, Shaanxi, Peoples R China 2.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 3.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging, Beijing 100190, Peoples R China 4.Northwest Univ Xian, Sch Informat Sci & Technol, Xian 710069, Peoples R China 5.Chinese Acad Sci, Inst Automat, State Key Lab Management & Control Complex Syst, Beijing 100190, Peoples R China |
第一作者单位 | 中国科学院自动化研究所 |
推荐引用方式 GB/T 7714 | Liu, Muhan,Guo, Hongbo,Liu, Hongbo,et al. In vivo pentamodal tomographic imaging for small animals[J]. BIOMEDICAL OPTICS EXPRESS,2017,8(3):1356-1371. |
APA | Liu, Muhan.,Guo, Hongbo.,Liu, Hongbo.,Zhang, Zeyu.,Chi, Chongwei.,...&Tian, Jie.(2017).In vivo pentamodal tomographic imaging for small animals.BIOMEDICAL OPTICS EXPRESS,8(3),1356-1371. |
MLA | Liu, Muhan,et al."In vivo pentamodal tomographic imaging for small animals".BIOMEDICAL OPTICS EXPRESS 8.3(2017):1356-1371. |
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