Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
| The combination design for open and endoscopic surgery using fluorescence molecular imaging technology | |
Yamin Mao1 ; Shixin Jiang2; Jinzuo Ye1; Yu An2; Xin Yang1; Chongwei Chi1; Jie Tian1
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| 2015-02 | |
| 会议名称 | SPIE Photonics West |
| 会议日期 | 2015.02.07-08 |
| 会议地点 | San Francisco |
| 摘要 | For clinical surgery, it is still a challenge to objectively determine tumor margins during surgery. With the development of medical imaging technology, fluorescence molecular imaging (FMI) method can provide real-time intraoperative tumor margin information. Furthermore, surgical navigation system based on FMI technology plays an important role for the aid of surgeons’ precise tumor margin decision. However, detection depth is the most limitation exists in the FMI technique and the method convenient for either macro superficial detection or micro deep tissue detection is needed. In this study, we combined advantages of both open surgery and endoscopic imaging systems with FMI technology. Indocyanine green (ICG) experiments were performed to confirm the feasibility of fluorescence detection in our system. Then, the ICG signal was photographed in the detection area with our system. When the system connected with endoscope lens, the minimum quantity of ICG detected by our system was 0.195 ug. For aspect of C mount lens, the sensitivity of ICG detection with our system was 0.195ug. Our experiments results proved that it was feasible to detect fluorescence images with this combination method. Our system shows great potential in the clinical applications of precise dissection of various tumors. |
| 关键词 | Intraoperative Image-guided Surgery Fluorescence Molecular Imaging Surgical Navigation System Indocyanine Green Endoscopy |
| 文献类型 | 会议论文 |
| 条目标识符 | http://ir.ia.ac.cn/handle/173211/21518 |
| 专题 | 中国科学院分子影像重点实验室 |
| 作者单位 | 1.Key Laboratory of Molecular Imaging, Institute of Chinese Academy of Sciences, Beijing 100190,China 2.The Department of Biomedical Engineering, School of Computer and Information Technology, Beijing Jiaotong University, Beijing 100044, China |
| 推荐引用方式 GB/T 7714 | Yamin Mao,Shixin Jiang,Jinzuo Ye,et al. The combination design for open and endoscopic surgery using fluorescence molecular imaging technology[C],2015. |
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| 文件名称/大小 | 文献类型 | 版本类型 | 开放类型 | 使用许可 | ||
| The Combination Desi（598KB） | 会议论文 | 开放获取 | CC BY-NC-SA | 浏览 下载 | ||
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