CASIA OpenIR
Automated brain extraction and immersive exploration of its layers in virtual reality for the rhesus macaque MRI data sets
Luo, Yanlin1; Gao, Bin2; Deng, Yiyi1; Zhu, Xiaoming1; Jiang, Tianzi2; Zhao, Xudong3; Yang, Zhengyi2
Source PublicationCOMPUTER ANIMATION AND VIRTUAL WORLDS
ISSN1546-4261
2019
Volume30Issue:1Pages:16
Corresponding AuthorYang, Zhengyi(zhengyi.yang@nlpr.ia.ac.cn)
AbstractAs we know, the rhesus macaque as a nonhuman primate is quite similar to a human being in genetics. Moreover, it has become essential in animal model anatomy and physiology in many modern medicine research such as the cardiovascular and cerebrovascular diseases in the recent years. This paper describes a pipeline from the raw rhesus macaque brain magnetic resonance imaging data to intuitive 3D inspection of its layers. Brain extraction is an initial step for subsequent analyses, but most of the existing methods so far are designed for human brain, which does not work well with the rhesus macaque. Firstly, we propose a reliable and efficient method to extract the brain from magnetic resonance imaging data sets based on dividing the brain into blocks. Then, we design a trapezoid opacity transfer function based on Compute Unified Device Architecture (CUDA)-based real-time volume ray casting, which is dedicated to volume rendering to make the inspection more intuitive. Besides, for an immersive exploration in virtual reality benefits understanding the volumetric data sets, so we also design a layer filter for the segmented rhesus macaque brain data sets, which facilitates the inspection of the interior in Region of Interest (ROI) by an intuitive bimanual interaction via a Leap Motion sensor. Our experiments prove usability and efficiency.
Keywordbimanual gesture interaction brain extraction rhesus macaque volume visualization 3D inspection
DOI10.1002/cav.1841
WOS KeywordVOLUME ; VISUALIZATION ; SEGMENTATION ; MORPHOMETRY
Indexed BySCI
Language英语
Funding ProjectStrategic Priority Research Program of the Chinese Academy of Sciences[XD-B02030300] ; Natural Science Foundation of China[91132301] ; Natural Science Foundation of China[91432302] ; National Social Science Foundation of China[BCA150050]
Funding OrganizationStrategic Priority Research Program of the Chinese Academy of Sciences ; Natural Science Foundation of China ; National Social Science Foundation of China
WOS Research AreaComputer Science
WOS SubjectComputer Science, Software Engineering
WOS IDWOS:000458275000006
PublisherWILEY
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/25304
Collection中国科学院自动化研究所
Corresponding AuthorYang, Zhengyi
Affiliation1.Beijing Normal Univ, Coll Informat Sci & Technol, Beijing, Peoples R China
2.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Beijing, Peoples R China
3.Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, Beijing, Peoples R China
Corresponding Author AffilicationInstitute of Automation, Chinese Academy of Sciences
Recommended Citation
GB/T 7714
Luo, Yanlin,Gao, Bin,Deng, Yiyi,et al. Automated brain extraction and immersive exploration of its layers in virtual reality for the rhesus macaque MRI data sets[J]. COMPUTER ANIMATION AND VIRTUAL WORLDS,2019,30(1):16.
APA Luo, Yanlin.,Gao, Bin.,Deng, Yiyi.,Zhu, Xiaoming.,Jiang, Tianzi.,...&Yang, Zhengyi.(2019).Automated brain extraction and immersive exploration of its layers in virtual reality for the rhesus macaque MRI data sets.COMPUTER ANIMATION AND VIRTUAL WORLDS,30(1),16.
MLA Luo, Yanlin,et al."Automated brain extraction and immersive exploration of its layers in virtual reality for the rhesus macaque MRI data sets".COMPUTER ANIMATION AND VIRTUAL WORLDS 30.1(2019):16.
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