The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12

	The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12
	Fang, Jiliang 1,2; Wang, Xiaoling1 ; Liu, Hesheng 2; Wang, Yin3 ; Zhou, Kehua 1,4; Hong, Yang 1; Liu, Jun 3; Wang, Lei1 ; Xue, Chao 1; Song, Ming5 ; Liu, Baoyan ; Zhu, Bing 6
发表期刊	EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
	2012
文章类型	Article
摘要	fMRI studies showed that acupuncture could induce hemodynamic changes in brain networks. Many of these studies focused on whether specific acupoints could activate specific brain regions and were often limited to manual acupuncture at acupoints on the limbs. In this fMRI study, we investigated acupuncture's modulation effects on brain functional networks by electroacupuncture (EA) at acupoints on the midline of abdomen. Acupoints Guanyuan (CV4) and Zhongwan (CV12) were stimulated in 21 healthy volunteers. The needling sensations, brain activation, and functional connectivity were studied. We found that the limbic-prefrontal functional network was deactivated by EA at CV4 and CV12. More importantly, the local functional connectivity was significantly changed during EA stimulation, and the change persisted during the period after the stimulation. Although minor differences existed, both acupoints similarly modulated the limbic-prefrontal functional network, which is overlapped with the functional circuits associated with emotional and cognitive regulation.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	INTRINSIC FUNCTIONAL CONNECTIVITY ; HUMAN BRAIN ; ACUPUNCTURE STIMULATION ; IMPLICATED ACUPOINTS ; CINGULATE CORTEX ; HEALTHY-SUBJECTS ; FMRI ; MRI ; ACTIVATION ; MECHANISM
收录类别	SCI
语种	英语
WOS研究方向	Integrative & Complementary Medicine
WOS类目	Integrative & Complementary Medicine
WOS记录号	WOS:000299532900001
引用统计	被引频次：18[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3201
专题	脑图谱与类脑智能实验室_脑网络组研究
作者单位	1.China Acad Chinese Med Sci, Funct Brain Imaging Lab, Dept Radiol, Guang An Men Hosp, Beijing 100053, Peoples R China 2.Harvard Univ, Sch Med, Athinoula A Martinos Ctr Biomed Imaging, Massachusetts Gen Hosp, Charlestown, MA 02129 USA 3.China Acad Chinese Med Sci, Dept Acupuncture & Moxibust, Guang An Men Hosp, Beijing 100053, Peoples R China 4.Daemen Coll, Dept Phys Therapy, Amherst, NY 14226 USA 5.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 6.China Acad Chinese Med Sci, Inst Acupuncture & Moxibust, Beijing 100700, Peoples R China
推荐引用方式 GB/T 7714	Fang, Jiliang,Wang, Xiaoling,Liu, Hesheng,et al. The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2012.
APA	Fang, Jiliang.,Wang, Xiaoling.,Liu, Hesheng.,Wang, Yin.,Zhou, Kehua.,...&Zhu, Bing.(2012).The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE.
MLA	Fang, Jiliang,et al."The Limbic-Prefrontal Network Modulated by Electroacupuncture at CV4 and CV12".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2012).