NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic

doi:10.1016/j.molmed.2020.02.003

	NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic
	Hu, Zhenhua1,2 ; Chen, Wen-Hua 3,4,5; Tian, Jie 1,2,6,7; Cheng, Zhen 4,5
发表期刊	TRENDS IN MOLECULAR MEDICINE
ISSN	1471-4914
	2020-05-01
卷号	26 期号:5 页码:469-482
通讯作者	Tian, Jie(jie.tian@ia.ac.cn) ; Cheng, Zhen(zcheng@stanford.edu)
摘要	Near-IR fluorescence imaging (NIRFI) is a highly promising technique for improving cancer theranostics in the era of precision medicine. Through the combination with cutting-edge bionanotechnologies, the potential of NIRFI can be greatly broadened. A variety of novel NIRF nanoprobes has been developed with ultimate goals of addressing unmet medical needs. Here, we present recent breakthroughs on the fundamental aspects of NIRFI, such as imaging at long wavelengths (1000-1700 nm), and the use of new approaches (X-rays, chemiluminescence, radioluminescence, etc.) for the excitation of novel nanoprobes. Within two decades, research on NIRF nanoprobes has translated to clinical trials and it will further translate to cancer management.
DOI	10.1016/j.molmed.2020.02.003
关键词[WOS]	IN-VIVO ; CERENKOV RADIATION ; FLUORESCENCE ; NANOPARTICLES ; LUMINESCENCE ; AFTERGLOW ; WINDOW ; NANOPHOSPHORS ; THERANOSTICS ; MODALITIES
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China[2017YFA0205200] ; National Key Research and Development Program of China[2016YFC0102600] ; National Natural Science Foundation of China (NSFC)[21877057] ; National Natural Science Foundation of China (NSFC)[81930053] ; National Natural Science Foundation of China (NSFC)[61622117] ; Beijing Nova Program[Z181100006218046] ; Jiangmen Program for Innovative Research Team[2018630100180019806] ; Department of Radiology, Stanford University
项目资助者	National Key Research and Development Program of China ; National Natural Science Foundation of China (NSFC) ; Beijing Nova Program ; Jiangmen Program for Innovative Research Team ; Department of Radiology, Stanford University
WOS研究方向	Biochemistry & Molecular Biology ; Cell Biology ; Research & Experimental Medicine
WOS类目	Biochemistry & Molecular Biology ; Cell Biology ; Medicine, Research & Experimental
WOS记录号	WOS:000532705900005
出版者	ELSEVIER SCI LTD
七大方向——子方向分类	医学影像处理与分析
引用统计	被引频次：55[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/39439
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie; Cheng, Zhen
作者单位	1.Chinese Acad Sci, CAS Key Lab Mol Imaging, State Key Lab Management & Control Complex Syst, Inst Automat,Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Wuyi Univ, Sch Biotechnol & Hlth Sci, Jiangmen 529020, Peoples R China 4.Stanford Univ, Sch Med, Dept Radiol, Bio X Program,MIPS, Stanford, CA 94305 USA 5.Stanford Univ, Sch Med, Stanford Canc Ctr, Stanford, CA 94305 USA 6.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Peoples R China 7.Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Beijing 100191, Peoples R China
第一作者单位	中国科学院分子影像重点实验室
通讯作者单位	中国科学院分子影像重点实验室
推荐引用方式 GB/T 7714	Hu, Zhenhua,Chen, Wen-Hua,Tian, Jie,et al. NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic[J]. TRENDS IN MOLECULAR MEDICINE,2020,26(5):469-482.
APA	Hu, Zhenhua,Chen, Wen-Hua,Tian, Jie,&Cheng, Zhen.(2020).NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic.TRENDS IN MOLECULAR MEDICINE,26(5),469-482.
MLA	Hu, Zhenhua,et al."NIRF Nanoprobes for Cancer Molecular Imaging: Approaching Clinic".TRENDS IN MOLECULAR MEDICINE 26.5(2020):469-482.