Fast and robust three-dimensional fluorescence source reconstruction based on separable approximation and adaptive regularization

	Fast and robust three-dimensional fluorescence source reconstruction based on separable approximation and adaptive regularization
	Xue, Zhenwen 1; Qin, Chenghu 1; Zhang, Qian2 ; Ma, Xibo1 ; Yang, Xin1 ; Tian, Jie 1,2
发表期刊	OPTICS COMMUNICATIONS
	2012-11-01
卷号	285 期号:24 页码:5570-5578
文章类型	Article
摘要	In this study, a fast and robust reconstruction method based on the separable approximation and the adaptive regularization is presented for fluorescence molecular tomography. The subproblems can be established and solved efficiently through separable approximation, and the convergence process can be also accelerated by adaptive regularization. As is well known, the regularization parameter has an important impact on the results, and finding the optimal or near-optimal regularization parameter automatically is an challenging task. To solve this problem, the regularization parameter in the proposed method is updated heuristically instead of being determined manually or empirically. This adaptive regularization strategy of the proposed method can perform accurate reconstruction almost without worrying about the choice of the regularization parameter. By contrast, improper choice of the regularization parameter may cause larger location errors for the three contrasting methods. The proposed method is proved robust and insensitive to parameters, which can improve the reconstruction accuracy. Moreover, the proposed method was about 1-2 orders of magnitude faster than the contrasting methods commonly used in fluorescence tomography reconstruction. Furthermore, reliable performance on different initial unknown values and different noise levels was also investigated. Finally, the potential of the proposed method in a practical application was further validated by the physical experiment with a mouse model. (C) 2012 Elsevier B.V. All rights reserved.
关键词	Fluorescence Molecular Tomography Inverse Problem Separable Approximation Adaptive Regularization
WOS标题词	Science & Technology ; Physical Sciences
关键词[WOS]	DIFFUSE OPTICAL TOMOGRAPHY ; BIOLUMINESCENCE TOMOGRAPHY ; SPARSITY REGULARIZATION ; MOLECULAR TOMOGRAPHY ; IMAGE-RECONSTRUCTION ; SCATTERING MEDIA ; LIGHT ; ALGORITHM
收录类别	SCI
语种	英语
WOS研究方向	Optics
WOS类目	Optics
WOS记录号	WOS:000311196500148
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/4103
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Chinese Acad Sci, Inst Automat, Intelligent Med Res Ctr, Beijing 100190, Peoples R China 2.Xidian Univ, Sch Life Sci & Technol, Life Sci Res Ctr, Xian 710069, Peoples R China
第一作者单位	中国科学院自动化研究所
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Xue, Zhenwen,Qin, Chenghu,Zhang, Qian,et al. Fast and robust three-dimensional fluorescence source reconstruction based on separable approximation and adaptive regularization[J]. OPTICS COMMUNICATIONS,2012,285(24):5570-5578.
APA	Xue, Zhenwen,Qin, Chenghu,Zhang, Qian,Ma, Xibo,Yang, Xin,&Tian, Jie.(2012).Fast and robust three-dimensional fluorescence source reconstruction based on separable approximation and adaptive regularization.OPTICS COMMUNICATIONS,285(24),5570-5578.
MLA	Xue, Zhenwen,et al."Fast and robust three-dimensional fluorescence source reconstruction based on separable approximation and adaptive regularization".OPTICS COMMUNICATIONS 285.24(2012):5570-5578.

条目包含的文件		下载所有文件
文件名称/大小	文献类型	版本类型	开放类型	使用许可
179.Optics Communica（1444KB）	期刊论文	作者接受稿	开放获取	CC BY-NC-SA	浏览下载