Clinical application of an automatic facial recognition system based on deep learning for diagnosis of Turner syndrome

doi:10.1007/s12020-020-02539-3

CASIA OpenIR > 多模态人工智能系统全国重点实验室 > 平行智能技术与系统团队

	Clinical application of an automatic facial recognition system based on deep learning for diagnosis of Turner syndrome
	Pan, Zhouxian 1; Shen, Zhen2,3 ; Zhu, Huijuan 4; Bao, Yin 2,5; Liang, Siyu 4; Wang, Shirui 4; Li, Xiangying 4; Niu, Lulu 2,6; Dong, Xisong2 ; Shang, Xiuqin2 ; Chen, Shi 4; Pan, Hui 4; Xiong, Gang2,7
发表期刊	ENDOCRINE
ISSN	1355-008X
	2020-11-10
页码	9
通讯作者	Chen, Shi(cspumch@163.com) ; Pan, Hui(panhui20111111@163.com) ; Xiong, Gang(gang.xiong@ia.ac.cn)
摘要	Purpose Automated facial recognition technology based on deep learning has achieved high accuracy in diagnosing various endocrine diseases and genetic syndromes. This study attempts to establish a facial diagnostic system for Turner syndrome (TS) based on deep convolutional neural networks. Methods Photographs of 207 TS patients and 1074 female controls were collected from July 2016 to April 2019. Finally, 170 patients diagnosed with TS and 1053 female controls were included. Deep convolutional neural networks were used to develop the facial diagnostic system. A prospective study, which included two TS patients and 35 controls, was conducted to test the efficacy in the real clinical setting. Results The average areas under the curve (AUCs) in three different scenarios were 0.9540 +/- 0.0223, 0.9662 +/- 0.0108 and 0.9557 +/- 0.0119, separately. The average sensitivity and specificity of the prospective study were 96.7% and 97.0%, respectively. Conclusions The facial diagnostic system achieved high accuracy. Prospective study results demonstrated the application value of this system, which is promising in the screening of Turner syndrome.
关键词	Facial pattern recognition Turner syndrome Deep convolutional neural network Prospective study
DOI	10.1007/s12020-020-02539-3
关键词[WOS]	AGE ; FEATURES
收录类别	SCI
语种	英语
资助项目	Beijing Municipal Natural Science Foundation[7192153] ; National Natural Science Foundation of China[61773382] ; National Natural Science Foundation of China[U190920015] ; National Natural Science Foundation of China[61773381] ; CAMS Initiative for Innovative Medicine[2016-I2M-1-008] ; CAS Key Technology Talent Program
项目资助者	Beijing Municipal Natural Science Foundation ; National Natural Science Foundation of China ; CAMS Initiative for Innovative Medicine ; CAS Key Technology Talent Program
WOS研究方向	Endocrinology & Metabolism
WOS类目	Endocrinology & Metabolism
WOS记录号	WOS:000588275600001
出版者	SPRINGER
七大方向——子方向分类	人工智能+医疗
引用统计	被引频次：14[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/41731
专题	多模态人工智能系统全国重点实验室_平行智能技术与系统团队
通讯作者	Chen, Shi; Pan, Hui; Xiong, Gang
作者单位	1.Chinese Acad Med Sci & Peking Union Med Coll CAMS, Peking Union Med Coll Hosp PUMCH, Dept Allergy, Beijing 100730, Peoples R China 2.Chinese Acad Sci, Inst Automat, Beijing Engn Res Ctr Intelligent Syst & Technol, State Key Lab Management & Control Complex Syst, Beijing 100190, Peoples R China 3.Qingdao Acad Intelligent Ind, Qingdao 266109, Peoples R China 4.CAMS & PUMC, PUMCH, Minist Hlth, Dept Endocrinol,Endocrine Key Lab, Beijing 100730, Peoples R China 5.Univ Southampton, Sch Elect & Comp Sci, Southampton SO17 1BJ, Hants, England 6.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 101408, Peoples R China 7.Chinese Acad Sci, Cloud Comp Ctr, Guangdong Engn Res Ctr 3D Printing & Intelligent, Dongguan 523808, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Pan, Zhouxian,Shen, Zhen,Zhu, Huijuan,et al. Clinical application of an automatic facial recognition system based on deep learning for diagnosis of Turner syndrome[J]. ENDOCRINE,2020:9.
APA	Pan, Zhouxian.,Shen, Zhen.,Zhu, Huijuan.,Bao, Yin.,Liang, Siyu.,...&Xiong, Gang.(2020).Clinical application of an automatic facial recognition system based on deep learning for diagnosis of Turner syndrome.ENDOCRINE,9.
MLA	Pan, Zhouxian,et al."Clinical application of an automatic facial recognition system based on deep learning for diagnosis of Turner syndrome".ENDOCRINE (2020):9.