Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm

doi:10.1364/PRJ.412884

	Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm
	Li, Huanhao 1,2; Woo, Chi Man 1,2; Zhong, Tianting 1,2; Yu, Zhipeng 1,2; Luo, Yunqi 3; Zheng, Yuanjin 3; Yang, Xin4 ; Hui, Hui4 ; Lai, Puxiang 1,2
发表期刊	PHOTONICS RESEARCH
ISSN	2327-9125
	2021-02-01
卷号	9 期号:2 页码:202-212
通讯作者	Hui, Hui(hui.hui@ia.ac.cn)
摘要	Optical imaging through or inside scattering media, such as multimode fiber and biological tissues, has a significant impact in biomedicine yet is considered challenging due to the strong scattering nature of light. In the past decade, promising progress has been made in the field, largely benefiting from the invention of iterative optical wavefront shaping, with which deep-tissue high-resolution optical focusing and hence imaging becomes possible. Most of the reported iterative algorithms can overcome small perturbations on the noise level but fail to effectively adapt beyond the noise level, e.g., sudden strong perturbations. Reoptimizations are usually needed for significant decorrelation to the medium since these algorithms heavily rely on the optimization performance in the previous iterations. Such ineffectiveness is probably due to the absence of a metric that can gauge the deviation of the instant wavefront from the optimum compensation based on the concurrently measured optical focusing. In this study, a square rule of binary-amplitude modulation, directly relating the measured focusing performance with the error in the optimized wavefront, is theoretically proved and experimentally validated. With this simple rule, it is feasible to quantify how many pixels on the spatial light modulator incorrectly modulate the wavefront for the instant status of the medium or the whole system. As an example of application, we propose a novel algorithm, the dynamic mutation algorithm, which has high adaptability against perturbations by probing how far the optimization has gone toward the theoretically optimal performance. The diminished focus of scattered light can be effectively recovered when perturbations to the medium cause a significant drop in the focusing performance, which no existing algorithms can achieve due to their inherent strong dependence on previous optimizations. With further improvement, the square rule and the new algorithm may boost or inspire many applications, such as high-resolution optical imaging and stimulation, in instable or dynamic scattering environments. (C) 2021 Chinese Laser Press
DOI	10.1364/PRJ.412884
关键词[WOS]	LIGHT ; OPTIMIZATION ; ENHANCEMENT
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[81627805] ; National Natural Science Foundation of China[81671726] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[81930048] ; Research Grants Council, University Grants Committee[25204416] ; Innovation and Technology Commission[GHP/043/19SZ] ; Innovation and Technology Commission[GHP/044/19GD] ; Innovation and Technology Commission[ITS/022/18] ; Guangdong Science and Technology Department[2019A1515011374] ; Guangdong Science and Technology Department[2019BT02X105] ; Science, Technology and Innovation Commission of Shenzhen Municipality[JCYJ20170818104421564] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences[2018167]
项目资助者	National Key Research and Development Program of China ; National Natural Science Foundation of China ; Research Grants Council, University Grants Committee ; Innovation and Technology Commission ; Guangdong Science and Technology Department ; Science, Technology and Innovation Commission of Shenzhen Municipality ; Youth Innovation Promotion Association of the Chinese Academy of Sciences
WOS研究方向	Optics
WOS类目	Optics
WOS记录号	WOS:000614927100017
出版者	CHINESE LASER PRESS
七大方向——子方向分类	其他
引用统计	被引频次：29[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/43321
专题	中国科学院分子影像重点实验室
通讯作者	Hui, Hui
作者单位	1.Hong Kong Polytech Univ, Dept Biomed Engn, Hong Kong, Peoples R China 2.Hong Kong Polytech Univ, Shenzhen Res Inst, Shenzhen, Peoples R China 3.Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore, Singapore 4.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Li, Huanhao,Woo, Chi Man,Zhong, Tianting,et al. Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm[J]. PHOTONICS RESEARCH,2021,9(2):202-212.
APA	Li, Huanhao.,Woo, Chi Man.,Zhong, Tianting.,Yu, Zhipeng.,Luo, Yunqi.,...&Lai, Puxiang.(2021).Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm.PHOTONICS RESEARCH,9(2),202-212.
MLA	Li, Huanhao,et al."Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm".PHOTONICS RESEARCH 9.2(2021):202-212.