Institutional Repository of Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
| Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm | |
Li, Huanhao1,2; Woo, Chi Man1,2; Zhong, Tianting1,2; Yu, Zhipeng1,2; Luo, Yunqi3; Zheng, Yuanjin3; Yang, Xin4 ; Hui, Hui4; Lai, Puxiang1,2
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| Source Publication | PHOTONICS RESEARCH
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| ISSN | 2327-9125 |
| 2021-02-01 | |
| Volume | 9Issue:2Pages:202-212 |
| Corresponding Author | Hui, Hui(hui.hui@ia.ac.cn) |
| Abstract | Optical imaging through or inside scattering media, such as multimode fiber and biological tissues, has a significant impact in biomedicine yet is considered challenging due to the strong scattering nature of light. In the past decade, promising progress has been made in the field, largely benefiting from the invention of iterative optical wavefront shaping, with which deep-tissue high-resolution optical focusing and hence imaging becomes possible. Most of the reported iterative algorithms can overcome small perturbations on the noise level but fail to effectively adapt beyond the noise level, e.g., sudden strong perturbations. Reoptimizations are usually needed for significant decorrelation to the medium since these algorithms heavily rely on the optimization performance in the previous iterations. Such ineffectiveness is probably due to the absence of a metric that can gauge the deviation of the instant wavefront from the optimum compensation based on the concurrently measured optical focusing. In this study, a square rule of binary-amplitude modulation, directly relating the measured focusing performance with the error in the optimized wavefront, is theoretically proved and experimentally validated. With this simple rule, it is feasible to quantify how many pixels on the spatial light modulator incorrectly modulate the wavefront for the instant status of the medium or the whole system. As an example of application, we propose a novel algorithm, the dynamic mutation algorithm, which has high adaptability against perturbations by probing how far the optimization has gone toward the theoretically optimal performance. The diminished focus of scattered light can be effectively recovered when perturbations to the medium cause a significant drop in the focusing performance, which no existing algorithms can achieve due to their inherent strong dependence on previous optimizations. With further improvement, the square rule and the new algorithm may boost or inspire many applications, such as high-resolution optical imaging and stimulation, in instable or dynamic scattering environments. (C) 2021 Chinese Laser Press |
| DOI | 10.1364/PRJ.412884 |
| WOS Keyword | LIGHT ; OPTIMIZATION ; ENHANCEMENT |
| Indexed By | SCI |
| Language | 英语 |
| Funding Project | National Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[81627805] ; National Natural Science Foundation of China[81671726] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[81930048] ; Research Grants Council, University Grants Committee[25204416] ; Innovation and Technology Commission[GHP/043/19SZ] ; Innovation and Technology Commission[GHP/044/19GD] ; Innovation and Technology Commission[ITS/022/18] ; Guangdong Science and Technology Department[2019A1515011374] ; Guangdong Science and Technology Department[2019BT02X105] ; Science, Technology and Innovation Commission of Shenzhen Municipality[JCYJ20170818104421564] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences[2018167] |
| Funding Organization | National Key Research and Development Program of China ; National Natural Science Foundation of China ; Research Grants Council, University Grants Committee ; Innovation and Technology Commission ; Guangdong Science and Technology Department ; Science, Technology and Innovation Commission of Shenzhen Municipality ; Youth Innovation Promotion Association of the Chinese Academy of Sciences |
| WOS Research Area | Optics |
| WOS Subject | Optics |
| WOS ID | WOS:000614927100017 |
| Publisher | CHINESE LASER PRESS |
| Sub direction classification | 其他 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.ia.ac.cn/handle/173211/43321 |
| Collection | 中国科学院分子影像重点实验室 |
| Corresponding Author | Hui, Hui |
| Affiliation | 1.Hong Kong Polytech Univ, Dept Biomed Engn, Hong Kong, Peoples R China 2.Hong Kong Polytech Univ, Shenzhen Res Inst, Shenzhen, Peoples R China 3.Nanyang Technol Univ, Sch Elect & Elect Engn, Singapore, Singapore 4.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing, Peoples R China |
| Corresponding Author Affilication | Institute of Automation, Chinese Academy of Sciences |
| Recommended Citation GB/T 7714 | Li, Huanhao,Woo, Chi Man,Zhong, Tianting,et al. Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm[J]. PHOTONICS RESEARCH,2021,9(2):202-212. |
| APA | Li, Huanhao.,Woo, Chi Man.,Zhong, Tianting.,Yu, Zhipeng.,Luo, Yunqi.,...&Lai, Puxiang.(2021).Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm.PHOTONICS RESEARCH,9(2),202-212. |
| MLA | Li, Huanhao,et al."Adaptive optical focusing through perturbed scattering media with a dynamic mutation algorithm".PHOTONICS RESEARCH 9.2(2021):202-212. |
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