Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment

doi:10.1016/j.isci.2023.107963

CASIA OpenIR > 脑图谱与类脑智能实验室

	Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment
	Yang, Binghao1,2 ; Zhang, Haoran 1,2; Jiang, Tianzi1,3,4 ; Yu, Shan1,2,3
发表期刊	ISCIENCE
	2023-10-20
卷号	26 期号:10 页码:17
通讯作者	Yu, Shan(shan.yu@nlpr.ia.ac.cn)
摘要	The delicate balance between cortical excitation and inhibition (E/I) plays a pivotal role in brain state changes. While previous studies have associated cortical hyperexcitability with brain state changes induced by sleep deprivation, whether cortical hypoexcitability is also linked to brain state changes and, if so, how it could affect cognitive performance remain unknown. Here, we address these questions by examining the brain state change occurring after meals, i.e., postprandial somnolence, and comparing it with that induced by sleep deprivation. By analyzing features representing network excitability based on electroencephalogram (EEG) signals, we confirmed cortical hyperexcitability under sleep deprivation but revealed hypoexcitability under postprandial somnolence. In addition, we found that both sleep deprivation and postprandial somnolence adversely affected the level of vigilance. These results indicate that cortical E/I balance toward inhibition is associated with brain state changes, and deviation from the balanced state, regardless of its direction, could impair cognitive performance.
DOI	10.1016/j.isci.2023.107963
关键词[WOS]	RANGE TEMPORAL CORRELATIONS ; THETA-BURST STIMULATION ; NEURONAL AVALANCHES ; CORTICAL NETWORKS ; SLEEP ; DYNAMICS ; EXCITATION ; WAKEFULNESS ; INCREASES ; MEMORY
收录类别	SCI
语种	英语
资助项目	International Partnership Program of the Chinese Academy of Sciences (CAS)[173211KYSB20200021] ; STI 2030-Major Project[2021ZD0200402] ; STI 2030-Major Project[2021ZD0200200]
项目资助者	International Partnership Program of the Chinese Academy of Sciences (CAS) ; STI 2030-Major Project
WOS研究方向	Science & Technology - Other Topics
WOS类目	Multidisciplinary Sciences
WOS记录号	WOS:001089060200001
出版者	CELL PRESS
引用统计
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/54332
专题	脑图谱与类脑智能实验室脑图谱与类脑智能实验室_脑机接口与融合智能
通讯作者	Yu, Shan
作者单位	1.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Lab Brain Atlas & Brain inspired Intelligence, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Future Technol, Beijing 101408, Peoples R China 3.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 101408, Peoples R China 4.Zhejiang Lab, Res Ctr Augmented Intelligence, Hangzhou 311121, Peoples R China
第一作者单位	中国科学院自动化研究所
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Yang, Binghao,Zhang, Haoran,Jiang, Tianzi,et al. Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment[J]. ISCIENCE,2023,26(10):17.
APA	Yang, Binghao,Zhang, Haoran,Jiang, Tianzi,&Yu, Shan.(2023).Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment.ISCIENCE,26(10),17.
MLA	Yang, Binghao,et al."Natural brain state change with E/I balance shifting toward inhibition is associated with vigilance impairment".ISCIENCE 26.10(2023):17.