Co-representation of Functional Brain Networks Is Shaped by Cortical Myeloarchitecture and Reveals Individual Behavioral Ability

doi:10.1523/JNEUROSCI.0856-23.2024

	Co-representation of Functional Brain Networks Is Shaped by Cortical Myeloarchitecture and Reveals Individual Behavioral Ability
	Chu, Congying1,2 ; Li, Wen1,3 ; Shi, Weiyang1 ; Wang, Haiyan1 ; Wang, Jiaojian 4; Liu, Yong5 ; Liu, Bing6 ; Elmenhorst, David 2; Eickhoff, Simon B.7,8; Fan, Lingzhong1,3,9 ; Jiang, Tianzi1,3,9,10,11
发表期刊	JOURNAL OF NEUROSCIENCE
ISSN	0270-6474
	2024-03-27
卷号	44 期号:13 页码:14
通讯作者	Fan, Lingzhong(lingzhong.fan@nlpr.ia.ac.cn) ; Jiang, Tianzi(jiangtz@nlpr.ia.ac.cn)
摘要	Large-scale functional networks are spatially distributed in the human brain. Despite recent progress in differentiating their functional roles, how the brain navigates the spatial coordination among them and the biological relevance of this coordination is still not fully understood. Capitalizing on canonical individualized networks derived from functional MRI data, we proposed a new concept, that is, co-representation of functional brain networks, to delineate the spatial coordination among them. To further quantify the co-representation pattern, we de fi ned two indexes, that is, the co-representation speci fi city (CoRS) and intensity (CoRI), for separately measuring the extent of speci fi c and average expression of functional networks at each brain location by using the data from both sexes. We found that the identi fi ed pattern of co-representation was anchored by cortical regions with three types of cytoarchitectural classes along a sensory - fugal axis, including, at the fi rst end, primary (idiotypic) regions showing high CoRS, at the second end, heteromodal regions showing low CoRS and high CoRI, at the third end, paralimbic regions showing low CoRI. Importantly, we demonstrated the critical role of myeloarchitecture in sculpting the spatial distribution of co-representation by assessing the association with the myelin-related neuroanatomical and transcriptomic pro fi les. Furthermore, the signi fi cance of manifesting the co-representation was revealed in its prediction of individual behavioral ability. Our fi ndings indicated that the spatial coordination among functional networks was built upon an anatomically con fi gured blueprint to facilitate neural information processing, while advancing our understanding of the topographical organization of the brain the of functional networks.
关键词	co-representation functional brain network myeloarchitecture resting-state fMRI
DOI	10.1523/JNEUROSCI.0856-23.2024
关键词[WOS]	INDEPENDENT COMPONENT ANALYSIS ; CONNECTIVITY ; CORTEX ; ATTENTION ; FMRI ; PSYCHOPATHOLOGY ; ORGANIZATION ; ARCHITECTURE ; ASSOCIATION ; TOPOGRAPHY
收录类别	SCI
语种	英语
资助项目	McDonnell Center for Systems Neuroscience at Washington University
项目资助者	McDonnell Center for Systems Neuroscience at Washington University
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:001240724800007
出版者	SOC NEUROSCIENCE
引用统计
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/58680
专题	脑图谱与类脑智能实验室_脑网络组研究
通讯作者	Fan, Lingzhong; Jiang, Tianzi
作者单位	1.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, Natl Lab Pattern Recognit, Beijing 100190, Peoples R China 2.Forschungszentrum Julich, Inst Neurosci & Med INM 2, D-52428 Julich, Germany 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Kunming Univ Sci & Technol, Inst Primate Translat Med, State Key Lab Primate Biomed Res, Kunming 650500, Peoples R China 5.Beijing Univ Posts & Telecommun, Sch Artificial Intelligence, Beijing 100876, Peoples R China 6.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China 7.Forschungszentrum Julich, Inst Neurosci & Med Brain & Behav INM 7, D-52428 Julich, Germany 8.Heinrich Heine Univ, Inst Syst Neurosci, Med Fac, D-40204 Dusseldorf, Germany 9.Chinese Acad Sci, Inst Automat, CAS Ctr Excellence Brain Sci & Intelligence Techno, Beijing 100049, Peoples R China 10.Xiaoxiang Inst Brain Hlth, Yongzhou 425000, Hunan, Peoples R China 11.Yongzhou Cent Hosp, Yongzhou 425000, Hunan, Peoples R China
第一作者单位	模式识别国家重点实验室
通讯作者单位	模式识别国家重点实验室; 中国科学院自动化研究所
推荐引用方式 GB/T 7714	Chu, Congying,Li, Wen,Shi, Weiyang,et al. Co-representation of Functional Brain Networks Is Shaped by Cortical Myeloarchitecture and Reveals Individual Behavioral Ability[J]. JOURNAL OF NEUROSCIENCE,2024,44(13):14.
APA	Chu, Congying.,Li, Wen.,Shi, Weiyang.,Wang, Haiyan.,Wang, Jiaojian.,...&Jiang, Tianzi.(2024).Co-representation of Functional Brain Networks Is Shaped by Cortical Myeloarchitecture and Reveals Individual Behavioral Ability.JOURNAL OF NEUROSCIENCE,44(13),14.
MLA	Chu, Congying,et al."Co-representation of Functional Brain Networks Is Shaped by Cortical Myeloarchitecture and Reveals Individual Behavioral Ability".JOURNAL OF NEUROSCIENCE 44.13(2024):14.