Characterizing the dynamic connectivity between genes by variable parameter regression and Kalman filtering based on temporal gene expression data

CASIA OpenIR > 09年以前成果

	Characterizing the dynamic connectivity between genes by variable parameter regression and Kalman filtering based on temporal gene expression data
	Cui, QH; Liu, B; Jiang, TX; Ma, SD
发表期刊	BIOINFORMATICS
	2005-04-15
卷号	21 期号:8 页码:1538-1541
文章类型	Article
摘要	Motivation: One popular method for analyzing functional connectivity between genes is to cluster genes with similar expression profiles. The most popular metrics measuring the similarity (or dissimilarity) among genes include Pearson's correlation, linear regression coefficient and Euclidean distance. As these metrics only give some constant values, they can only depict a stationary connectivity between genes. However, the functional connectivity between genes usually changes with time. Here, we introduce a novel insight for characterizing the relationship between genes and find out a proper mathematical model, variable parameter regression and Kalman filtering to model it.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Technology ; Physical Sciences
关键词[WOS]	CELL-CYCLE
收录类别	SCI
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Computer Science ; Mathematical & Computational Biology ; Mathematics
WOS类目	Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Computer Science, Interdisciplinary Applications ; Mathematical & Computational Biology ; Statistics & Probability
WOS记录号	WOS:000228401800037
引用统计	被引频次：7[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/9138
专题	09年以前成果
作者单位	Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Cui, QH,Liu, B,Jiang, TX,et al. Characterizing the dynamic connectivity between genes by variable parameter regression and Kalman filtering based on temporal gene expression data[J]. BIOINFORMATICS,2005,21(8):1538-1541.
APA	Cui, QH,Liu, B,Jiang, TX,&Ma, SD.(2005).Characterizing the dynamic connectivity between genes by variable parameter regression and Kalman filtering based on temporal gene expression data.BIOINFORMATICS,21(8),1538-1541.
MLA	Cui, QH,et al."Characterizing the dynamic connectivity between genes by variable parameter regression and Kalman filtering based on temporal gene expression data".BIOINFORMATICS 21.8(2005):1538-1541.