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Single-trial variable model for event-related fMRI data analysis
Lu, YL; Jiang, TZ; Zang, YF
2005-02-01
发表期刊IEEE TRANSACTIONS ON MEDICAL IMAGING
卷号24期号:2页码:236-245
文章类型Article
摘要Most methods for fMRI data analysis assume that the hemodynamic responses (HRs) across similar experimental events are same. This assumption is not appropriate when HRs vary unpredictably from trial to trial. Here, we introduce a new method for fMRI data analysis. The main features of the proposed method are as follows: 1) The trial-to-trial variability is modeled as meaningful signal rather than assuming that the same HR is evoked in each trial; 2) Since the proposed method is a constrained optimization based general framework, it could be extended by utilizing prior knowledge of HR; 3) The traditional deconvolution method can be included into our method as a special case. A comparison of performance on simulated fMRI datasets is made using the general linear model, the deconvolution method and the proposed method with receiver operating characteristic (ROC) methodology. In addition, we examined the effectiveness and usefulness of our method on real experimental data.
关键词Brain Deconvolution Functional Mri General Linear Model
WOS标题词Science & Technology ; Technology ; Life Sciences & Biomedicine
关键词[WOS]INDEPENDENT COMPONENT ANALYSIS ; HUMAN BRAIN ; FUNCTIONAL MRI ; TIME-SERIES ; ACTIVATION ; DECONVOLUTION ; VARIABILITY ; RESPONSES ; SIGNALS
收录类别SCI
语种英语
WOS研究方向Computer Science ; Engineering ; Imaging Science & Photographic Technology ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目Computer Science, Interdisciplinary Applications ; Engineering, Biomedical ; Engineering, Electrical & Electronic ; Imaging Science & Photographic Technology ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号WOS:000226697800010
引用统计
被引频次:9[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9183
专题09年以前成果
作者单位Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China
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Lu, YL,Jiang, TZ,Zang, YF. Single-trial variable model for event-related fMRI data analysis[J]. IEEE TRANSACTIONS ON MEDICAL IMAGING,2005,24(2):236-245.
APA Lu, YL,Jiang, TZ,&Zang, YF.(2005).Single-trial variable model for event-related fMRI data analysis.IEEE TRANSACTIONS ON MEDICAL IMAGING,24(2),236-245.
MLA Lu, YL,et al."Single-trial variable model for event-related fMRI data analysis".IEEE TRANSACTIONS ON MEDICAL IMAGING 24.2(2005):236-245.
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