Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging

CASIA OpenIR > 09年以前成果

	Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging
	Liang, M; Zhou, Y ; Jiang, TZ; Liu, ZN ; Tian, LX ; Liu, HH ; Hao, YH
发表期刊	NEUROREPORT
	2006-02-06
卷号	17 期号:2 页码:209-213
文章类型	Article
摘要	Using resting-state functional magnetic resonance imaging, we examined the functional connectivity throughout the entire brain in schizophrenia. The abnormalities in functional connectivity were identified by comparing the correlation coefficients of each pair of 116 brain regions between 15 patients and 15 controls. Then, the global distribution of the abnormal functional connectivities was examined. Experimental results indicated, in general, a decreased functional connectivity in schizophrenia during rest, and such abnormalities were widely distributed throughout the entire brain rather than restricted to a few specific brain regions. The results provide a quantitative support for the hypothesis that schizophrenia may arise from the disrupted functional integration of widespread brain areas.
关键词	Functional Connectivity Functional Magnetic Resonance Imaging Resting State Schizophrenia
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	HUMAN BRAIN ; 1ST-EPISODE SCHIZOPHRENIA ; MOTOR CORTEX ; CONNECTIVITY ; IMAGES ; FMRI ; MRI ; FLUCTUATIONS ; SINGLE
收录类别	SCI
语种	英语
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:000235349800020
引用统计	被引频次：325[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/9232
专题	09年以前成果
作者单位	1.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China 2.Cent S Univ, Xiangya Hosp 2, Inst Mental Hlth, Changsha 410083, Hunan, Peoples R China
推荐引用方式 GB/T 7714	Liang, M,Zhou, Y,Jiang, TZ,et al. Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging[J]. NEUROREPORT,2006,17(2):209-213.
APA	Liang, M.,Zhou, Y.,Jiang, TZ.,Liu, ZN.,Tian, LX.,...&Hao, YH.(2006).Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging.NEUROREPORT,17(2),209-213.
MLA	Liang, M,et al."Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging".NEUROREPORT 17.2(2006):209-213.