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Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging
Liang, M; Zhou, Y; Jiang, TZ; Liu, ZN; Tian, LX; Liu, HH; Hao, YH
2006-02-06
发表期刊NEUROREPORT
卷号17期号:2页码:209-213
文章类型Article
摘要Using resting-state functional magnetic resonance imaging, we examined the functional connectivity throughout the entire brain in schizophrenia. The abnormalities in functional connectivity were identified by comparing the correlation coefficients of each pair of 116 brain regions between 15 patients and 15 controls. Then, the global distribution of the abnormal functional connectivities was examined. Experimental results indicated, in general, a decreased functional connectivity in schizophrenia during rest, and such abnormalities were widely distributed throughout the entire brain rather than restricted to a few specific brain regions. The results provide a quantitative support for the hypothesis that schizophrenia may arise from the disrupted functional integration of widespread brain areas.
关键词Functional Connectivity Functional Magnetic Resonance Imaging Resting State Schizophrenia
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]HUMAN BRAIN ; 1ST-EPISODE SCHIZOPHRENIA ; MOTOR CORTEX ; CONNECTIVITY ; IMAGES ; FMRI ; MRI ; FLUCTUATIONS ; SINGLE
收录类别SCI
语种英语
WOS研究方向Neurosciences & Neurology
WOS类目Neurosciences
WOS记录号WOS:000235349800020
引用统计
被引频次:266[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9232
专题09年以前成果
作者单位1.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China
2.Cent S Univ, Xiangya Hosp 2, Inst Mental Hlth, Changsha 410083, Hunan, Peoples R China
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GB/T 7714
Liang, M,Zhou, Y,Jiang, TZ,et al. Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging[J]. NEUROREPORT,2006,17(2):209-213.
APA Liang, M.,Zhou, Y.,Jiang, TZ.,Liu, ZN.,Tian, LX.,...&Hao, YH.(2006).Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging.NEUROREPORT,17(2),209-213.
MLA Liang, M,et al."Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging".NEUROREPORT 17.2(2006):209-213.
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