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White matter integrity of the whole brain is disrupted in first-episode schizophrenia | |
Hao, YH; Liu, ZN; Jiang, TZ![]() | |
发表期刊 | NEUROREPORT
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2006-01-23 | |
卷号 | 17期号:1页码:23-26 |
文章类型 | Article |
摘要 | Diffusion tensor imaging studies in schizophrenia have demonstrated lower diffusion anisotropy within white matter that provides information about brain white matter integrity. We have examined whether white matter is abnormal in first-episode schizophrenia by using diffusion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent diffusion tensor imaging scans that analyzed by using a rigorous voxel-based approach. We found that fractional anisotropy in white matter of the patients was lower than that in controls at the cerebral pecluncle, frontal regions, inferior temporal gyrus, medial parietal lobes, hippocampal gyrus, insula, right anterior cingulum bundle and right corona radiata. These results suggested that white matter integrity of the whole brain was disrupted in early illness onset of schizophrenia. |
关键词 | Diffusion Tensor Imaging First-episode Schizophrenia Fractional Anisotropy White Matter |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
关键词[WOS] | DIFFUSION ANISOTROPY ; ANTERIOR CINGULUM ; CORPUS-CALLOSUM ; WORKING-MEMORY ; ABNORMALITIES ; MRI ; CORTEX |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Neurosciences & Neurology |
WOS类目 | Neurosciences |
WOS记录号 | WOS:000234527700006 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/9383 |
专题 | 09年以前成果 |
作者单位 | 1.Cent S Univ, Inst Mental Hlth, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Hunan, Peoples R China 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing, Peoples R China 3.Chinese Acad Sci, Lab Learning & Memory, Kunming Inst Zool, Yunnan, Peoples R China |
推荐引用方式 GB/T 7714 | Hao, YH,Liu, ZN,Jiang, TZ,et al. White matter integrity of the whole brain is disrupted in first-episode schizophrenia[J]. NEUROREPORT,2006,17(1):23-26. |
APA | Hao, YH.,Liu, ZN.,Jiang, TZ.,Gong, GL.,Liu, HH.,...&Zhang, ZS.(2006).White matter integrity of the whole brain is disrupted in first-episode schizophrenia.NEUROREPORT,17(1),23-26. |
MLA | Hao, YH,et al."White matter integrity of the whole brain is disrupted in first-episode schizophrenia".NEUROREPORT 17.1(2006):23-26. |
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