CASIA OpenIR  > 09年以前成果
Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD
Hou, Cailan; Liu, Jun; Wang, Kun; Li, Lingjiang; Liang, Meng; He, Zhong; Liu, Yong; Zhang, Yan; Li, Weihui; Jiang, Tianzi
Source PublicationBRAIN RESEARCH
2007-05-04
Volume1144Pages:165-174
SubtypeArticle
AbstractFunctional neuroimaging studies have largely been performed in patients with longstanding chronic posttraumatic stress disorder (PTSD). Additionally, memory function of PTSD patients has been proved to be impaired. We sought to characterize the brain responses of patients with acute PTSD and implemented a trauma-related short-term memory recall paradigm. Individuals with acute severe PTSD (n = 10) resulting from a mining accident and 7 men exposed to the mining accident without PTSD underwent functional magnetic resonance imaging (fMRI) while performing the symptom provocation and trauma-related short-term memory recall paradigms. During symptom provocation paradigm, PTSD subjects showed diminished responses in right anterior cingulate gyrus, left inferior frontal gyrus and bilateral middle frontal gyrus and enhanced left parahippocampal. gyrus response compared with controls. During the short-term memory recall paradigm, PTSD group showed diminished responses in right inferior frontal gyrus, right middle frontal and left middle occipital gyrus in comparison with controls. PTSD group exhibited diminished right parahippocampal gyrus response during the memory recall task as compared to the symptom provocation task. Our findings suggest that neurophysiological alterations and memory performance deficit have developed in acute severe PTSD. (c) 2007 Elsevier B.V. All rights reserved.
KeywordCoal Mining Accident Acute Severe Ptsd Fmri
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
WOS KeywordPOSTTRAUMATIC-STRESS-DISORDER ; MEDIAL PREFRONTAL CORTEX ; ANTERIOR CINGULATE CORTEX ; CHILDHOOD SEXUAL-ABUSE ; SCRIPT-DRIVEN IMAGERY ; POSITRON-EMISSION-TOMOGRAPHY ; CEREBRAL-BLOOD-FLOW ; FUNCTIONAL MRI ; HIPPOCAMPAL VOLUME ; AMYGDALA RESPONSE
Indexed BySCI ; SSCI
Language英语
WOS Research AreaNeurosciences & Neurology
WOS SubjectNeurosciences
WOS IDWOS:000246034100019
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/9388
Collection09年以前成果
Affiliation1.Chinese Acad Sci, Inst Automat, Med Imaging & Cop Natl Lab, Beijing 100080, Peoples R China
2.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha 410011, Hunan, Peoples R China
3.Cent S Univ, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Hunan, Peoples R China
Recommended Citation
GB/T 7714
Hou, Cailan,Liu, Jun,Wang, Kun,et al. Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD[J]. BRAIN RESEARCH,2007,1144:165-174.
APA Hou, Cailan.,Liu, Jun.,Wang, Kun.,Li, Lingjiang.,Liang, Meng.,...&Jiang, Tianzi.(2007).Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD.BRAIN RESEARCH,1144,165-174.
MLA Hou, Cailan,et al."Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD".BRAIN RESEARCH 1144(2007):165-174.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Hou, Cailan]'s Articles
[Liu, Jun]'s Articles
[Wang, Kun]'s Articles
Baidu academic
Similar articles in Baidu academic
[Hou, Cailan]'s Articles
[Liu, Jun]'s Articles
[Wang, Kun]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Hou, Cailan]'s Articles
[Liu, Jun]'s Articles
[Wang, Kun]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.