Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD

CASIA OpenIR > 09年以前成果

	Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD
	Hou, Cailan ; Liu, Jun ; Wang, Kun ; Li, Lingjiang ; Liang, Meng ; He, Zhong ; Liu, Yong; Zhang, Yan ; Li, Weihui ; Jiang, Tianzi
发表期刊	BRAIN RESEARCH
	2007-05-04
卷号	1144 页码:165-174
文章类型	Article
摘要	Functional neuroimaging studies have largely been performed in patients with longstanding chronic posttraumatic stress disorder (PTSD). Additionally, memory function of PTSD patients has been proved to be impaired. We sought to characterize the brain responses of patients with acute PTSD and implemented a trauma-related short-term memory recall paradigm. Individuals with acute severe PTSD (n = 10) resulting from a mining accident and 7 men exposed to the mining accident without PTSD underwent functional magnetic resonance imaging (fMRI) while performing the symptom provocation and trauma-related short-term memory recall paradigms. During symptom provocation paradigm, PTSD subjects showed diminished responses in right anterior cingulate gyrus, left inferior frontal gyrus and bilateral middle frontal gyrus and enhanced left parahippocampal. gyrus response compared with controls. During the short-term memory recall paradigm, PTSD group showed diminished responses in right inferior frontal gyrus, right middle frontal and left middle occipital gyrus in comparison with controls. PTSD group exhibited diminished right parahippocampal gyrus response during the memory recall task as compared to the symptom provocation task. Our findings suggest that neurophysiological alterations and memory performance deficit have developed in acute severe PTSD. (c) 2007 Elsevier B.V. All rights reserved.
关键词	Coal Mining Accident Acute Severe Ptsd Fmri
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	POSTTRAUMATIC-STRESS-DISORDER ; MEDIAL PREFRONTAL CORTEX ; ANTERIOR CINGULATE CORTEX ; CHILDHOOD SEXUAL-ABUSE ; SCRIPT-DRIVEN IMAGERY ; POSITRON-EMISSION-TOMOGRAPHY ; CEREBRAL-BLOOD-FLOW ; FUNCTIONAL MRI ; HIPPOCAMPAL VOLUME ; AMYGDALA RESPONSE
收录类别	SCI ; SSCI
语种	英语
WOS研究方向	Neurosciences & Neurology
WOS类目	Neurosciences
WOS记录号	WOS:000246034100019
引用统计	被引频次：71[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/9388
专题	09年以前成果
作者单位	1.Chinese Acad Sci, Inst Automat, Med Imaging & Cop Natl Lab, Beijing 100080, Peoples R China 2.Cent S Univ, Xiangya Hosp 2, Mental Hlth Inst, Changsha 410011, Hunan, Peoples R China 3.Cent S Univ, Xiangya Hosp 2, Dept Radiol, Changsha 410011, Hunan, Peoples R China
推荐引用方式 GB/T 7714	Hou, Cailan,Liu, Jun,Wang, Kun,et al. Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD[J]. BRAIN RESEARCH,2007,1144:165-174.
APA	Hou, Cailan.,Liu, Jun.,Wang, Kun.,Li, Lingjiang.,Liang, Meng.,...&Jiang, Tianzi.(2007).Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD.BRAIN RESEARCH,1144,165-174.
MLA	Hou, Cailan,et al."Brain responses to symptom provocation and trauma-related short-term memory recall in coal mining accident survivors with acute severe PTSD".BRAIN RESEARCH 1144(2007):165-174.