Alignment of two-dimensional electrophoresis gels

CASIA OpenIR > 09年以前成果

	Alignment of two-dimensional electrophoresis gels
	Shi, Guihua; Jiang, Tianzi; Zhu, Wanlin; Liu, Bing; Zhao, Huizhi
发表期刊	BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
	2007-06-01
卷号	357 期号:2 页码:427-432
文章类型	Article
摘要	Two-dimensional electrophoresis is a major separating technique for proteins in proteomics. Alignment of gel images is critical for intra-laboratory or even more difficult inter-laboratory gel comparisons. In the paper, we propose a novel iterative closest point (ICP) method for 2D-gel electrophoresis image alignment. The paper seeks to introduce an information theoretic measure as one part of distance metric to gel image alignment. We combine intensity information of spots with geometric information of landmarks by applying information potential idea. The proposed method has been applied to both synthetic and real gel images accessible in public 2D-electrophoresis gel protein databases. The high accuracy and robustness of the algorithm indicate that it is promising for gel image alignment. (c) 2007 Elsevier Inc. All rights reserved.
关键词	2d-gel Electrophoresis Image Image Alignment Icp Algorithm Informational Potential
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	ELASTIC REGISTRATION ; IMAGE REGISTRATION ; INFORMATION
收录类别	SCI
语种	英语
WOS研究方向	Biochemistry & Molecular Biology ; Biophysics
WOS类目	Biochemistry & Molecular Biology ; Biophysics
WOS记录号	WOS:000246253700017
引用统计	被引频次：11[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/9423
专题	09年以前成果
作者单位	Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100080, Peoples R China
推荐引用方式 GB/T 7714	Shi, Guihua,Jiang, Tianzi,Zhu, Wanlin,et al. Alignment of two-dimensional electrophoresis gels[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,2007,357(2):427-432.
APA	Shi, Guihua,Jiang, Tianzi,Zhu, Wanlin,Liu, Bing,&Zhao, Huizhi.(2007).Alignment of two-dimensional electrophoresis gels.BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS,357(2),427-432.
MLA	Shi, Guihua,et al."Alignment of two-dimensional electrophoresis gels".BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 357.2(2007):427-432.