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Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies | |
Liu, Yong1; Wang, Kun1; Yu, Chunshui2; He, Yong1,3; Zhou, Yuan1; Liang, Meng1,4; Wang, Liang2; Jiang, Tianzi1; Jiang Tianzi | |
发表期刊 | NEUROPSYCHOLOGIA |
2008 | |
卷号 | 46期号:6页码:1648-1656 |
文章类型 | Review |
摘要 | Resting-state functional magnetic resonance imaging (fMRI), a promising technique for measuring brain activities during rest, has attracted much attention in the past few years. In this paper, we review recent progress on the study of Alzheimer's disease (AD) based on resting-state fMRI. First, we briefly introduce some AD-related studies from other groups. Then we describe our AD-related work in detail from three aspects: (1) alterations in regional homogeneity (ReHo) of the fMRI signal in the resting state, (2) altered patterns of functional connectivity from regions of interest and whole brain analyses, and (3) discriminative analyses based on classification features from resting-state fMRI data for differentiating AD patients from healthy elders. Finally, we summarize the main results and some prospects for future work. (c) 2008 Published by Elsevier Ltd. |
关键词 | Alzheimer's Disease Resting-state Fmri Reho Functional Connectivity Biomarkers |
WOS标题词 | Science & Technology ; Social Sciences ; Life Sciences & Biomedicine |
关键词[WOS] | MILD COGNITIVE IMPAIRMENT ; INDEPENDENT COMPONENT ANALYSIS ; POSITRON-EMISSION-TOMOGRAPHY ; MAGNETIC-RESONANCE ; BRAIN ACTIVITY ; DEFAULT-MODE ; FDG-PET ; DISCONNECTION SYNDROME ; CINGULATE CORTEX ; NETWORK ANALYSIS |
收录类别 | SCI ; SSCi |
语种 | 英语 |
WOS研究方向 | Behavioral Sciences ; Neurosciences & Neurology ; Psychology |
WOS类目 | Behavioral Sciences ; Neurosciences ; Psychology, Experimental |
WOS记录号 | WOS:000257128200007 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/9609 |
专题 | 09年以前成果 |
通讯作者 | Jiang Tianzi |
作者单位 | 1.Chinese Acad Sci, Natl Lab Pattern Recognit, Inst Automat, Beijing 100190, Peoples R China 2.Capital Med Univ, Xuanwu Hosp, Dept Radiol, Beijing 100053, Peoples R China 3.McGill Univ, Montreal Neurol Inst, McConnell Brain Imaging Ctr, Montreal, PQ H3A 2B4, Canada 4.Univ Oxford, Dept Physiol Anat & Genet, Oxford OX1 3QX, England |
第一作者单位 | 模式识别国家重点实验室 |
推荐引用方式 GB/T 7714 | Liu, Yong,Wang, Kun,Yu, Chunshui,et al. Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies[J]. NEUROPSYCHOLOGIA,2008,46(6):1648-1656. |
APA | Liu, Yong.,Wang, Kun.,Yu, Chunshui.,He, Yong.,Zhou, Yuan.,...&Jiang Tianzi.(2008).Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies.NEUROPSYCHOLOGIA,46(6),1648-1656. |
MLA | Liu, Yong,et al."Regional homogeneity, functional connectivity and imaging markers of Alzheimer's disease: A review of resting-state fMRI studies".NEUROPSYCHOLOGIA 46.6(2008):1648-1656. |
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