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Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study
Gong, Gaolang1; Shi, Feng3; Concha, Luis1; Beaulieu, Christian1; Gross, Donald W.2
2008-11-01
发表期刊EPILEPSIA
卷号49期号:11页码:1941-1945
文章类型Article
摘要While acute hippocampal magnetic resonance imaging (MRI) changes have been demonstrated, the long-term structural consequence of status epilepticus remains unclear. Also the timing of previously reported fornix abnormalities in patients with mesial temporal sclerosis (MTS) is unknown. We report longitudinal volumetic MRI and diffusion tensor imaging (DTI) findings of the hippocampus and fornix in a patient following status epilepticus. Left hippocampal atrophy demonstrated progression beyond 6 months poststatus epilepticus while the right hippocampus and bilateral fornices demonstrated stable volumetric and diffusion abnormalities throughout the study. Our findings provide evidence that status epilepticus can induce permanent hippocampal damage with the delayed timing of the structural changes being consistent with programmed cell death.
关键词Status Epilepticus Hippocampus Fornix
WOS标题词Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]GENERALIZED STATUS EPILEPTICUS ; EPILEPSY ; ABNORMALITIES ; EVOLUTION ; DAMAGE
收录类别SCI
语种英语
WOS研究方向Neurosciences & Neurology
WOS类目Clinical Neurology
WOS记录号WOS:000260744200012
引用统计
被引频次:11[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/9627
专题09年以前成果
作者单位1.Univ Alberta, Dept Biomed Engn, Edmonton, AB, Canada
2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100864, Peoples R China
3.Univ Alberta, Dept Med, Div Neurol, Edmonton, AB, Canada
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Gong, Gaolang,Shi, Feng,Concha, Luis,et al. Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study[J]. EPILEPSIA,2008,49(11):1941-1945.
APA Gong, Gaolang,Shi, Feng,Concha, Luis,Beaulieu, Christian,&Gross, Donald W..(2008).Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study.EPILEPSIA,49(11),1941-1945.
MLA Gong, Gaolang,et al."Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study".EPILEPSIA 49.11(2008):1941-1945.
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