Knowledge Commons of Institute of Automation,CAS
Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study | |
Gong, Gaolang1; Shi, Feng3; Concha, Luis1; Beaulieu, Christian1; Gross, Donald W.2 | |
发表期刊 | EPILEPSIA |
2008-11-01 | |
卷号 | 49期号:11页码:1941-1945 |
文章类型 | Article |
摘要 | While acute hippocampal magnetic resonance imaging (MRI) changes have been demonstrated, the long-term structural consequence of status epilepticus remains unclear. Also the timing of previously reported fornix abnormalities in patients with mesial temporal sclerosis (MTS) is unknown. We report longitudinal volumetic MRI and diffusion tensor imaging (DTI) findings of the hippocampus and fornix in a patient following status epilepticus. Left hippocampal atrophy demonstrated progression beyond 6 months poststatus epilepticus while the right hippocampus and bilateral fornices demonstrated stable volumetric and diffusion abnormalities throughout the study. Our findings provide evidence that status epilepticus can induce permanent hippocampal damage with the delayed timing of the structural changes being consistent with programmed cell death. |
关键词 | Status Epilepticus Hippocampus Fornix |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
关键词[WOS] | GENERALIZED STATUS EPILEPTICUS ; EPILEPSY ; ABNORMALITIES ; EVOLUTION ; DAMAGE |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Neurosciences & Neurology |
WOS类目 | Clinical Neurology |
WOS记录号 | WOS:000260744200012 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/9627 |
专题 | 09年以前成果 |
作者单位 | 1.Univ Alberta, Dept Biomed Engn, Edmonton, AB, Canada 2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100864, Peoples R China 3.Univ Alberta, Dept Med, Div Neurol, Edmonton, AB, Canada |
推荐引用方式 GB/T 7714 | Gong, Gaolang,Shi, Feng,Concha, Luis,et al. Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study[J]. EPILEPSIA,2008,49(11):1941-1945. |
APA | Gong, Gaolang,Shi, Feng,Concha, Luis,Beaulieu, Christian,&Gross, Donald W..(2008).Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study.EPILEPSIA,49(11),1941-1945. |
MLA | Gong, Gaolang,et al."Insights into the sequence of structural consequences of convulsive status epilepticus: A longitudinal MRI study".EPILEPSIA 49.11(2008):1941-1945. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论