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Cell image segmentation with kernel-based dynamic clustering and an ellipsoidal cell shape model | |
Yang, FG; Jiang, TZ![]() | |
发表期刊 | JOURNAL OF BIOMEDICAL INFORMATICS
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2001-04-01 | |
卷号 | 34期号:2页码:67-73 |
文章类型 | Article |
摘要 | In this paper, we propose a novel approach to cell image segmentation under severe noise conditions by combining kernel-based dynamic clustering and a genetic algorithm. Our method incorporates a priori knowledge about cell shape. That is, an elliptical cell contour model is introduced to describe the boundary of the cell. Our method consists of the following components: (1) obtain the gradient image; (2) use the gradient image to obtain points which possibly belong to cell boundaries; (3) adjust the parameters of the elliptical cell boundary model to match the cell contour using a genetic algorithm. The method is tested on images of noisy human thyroid and small intestine cells. (C) 2001 Academic Press. |
关键词 | Cell Images Image Segmentation Quantitative Pathology Genetic Algorithms |
WOS标题词 | Science & Technology ; Technology ; Life Sciences & Biomedicine |
关键词[WOS] | ALGORITHM |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Computer Science ; Medical Informatics |
WOS类目 | Computer Science, Interdisciplinary Applications ; Medical Informatics |
WOS记录号 | WOS:000170378600001 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/9837 |
专题 | 09年以前成果 |
作者单位 | 1.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, Beijing 100080, Peoples R China 2.Queens Univ Belfast, Sch Comp Sci, Belfast BT7 1NN, Antrim, North Ireland |
推荐引用方式 GB/T 7714 | Yang, FG,Jiang, TZ. Cell image segmentation with kernel-based dynamic clustering and an ellipsoidal cell shape model[J]. JOURNAL OF BIOMEDICAL INFORMATICS,2001,34(2):67-73. |
APA | Yang, FG,&Jiang, TZ.(2001).Cell image segmentation with kernel-based dynamic clustering and an ellipsoidal cell shape model.JOURNAL OF BIOMEDICAL INFORMATICS,34(2),67-73. |
MLA | Yang, FG,et al."Cell image segmentation with kernel-based dynamic clustering and an ellipsoidal cell shape model".JOURNAL OF BIOMEDICAL INFORMATICS 34.2(2001):67-73. |
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