CASIA OpenIR  > 类脑智能研究中心  > 神经计算及脑机交互
An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images
Xie, Qiwei1,2,3; Chen, Xi3; Deng, Hao4; Liu, Danqian5; Sun, Yingyu6; Zhou, Xiaojuan6; Yang, Yang5,7; Han, Hua3,7,8
Source PublicationBIODATA MINING
2017-12-20
Volume10Issue:10Pages:40
SubtypeArticle
AbstractBackground: In the nervous system, the neurons communicate through synapses. The size, morphology, and connectivity of these synapses are significant in determining the functional properties of the neural network. Therefore, they have always been a major focus of neuroscience research. Two-photon laser scanning microscopy allows the visualization of synaptic structures in vivo, leading to many important findings. However, the identification and quantification of structural imaging data currently rely heavily on manual annotation, a method that is both time-consuming and prone to bias.
KeywordIn Vivo Two-photon imagIng Synapse Bouton Spine Image Enhancement
WOS HeadingsScience & Technology ; Life Sciences & Biomedicine
DOI10.1186/s13040-017-0161-5
WOS KeywordDENDRITIC SPINES ; SEGMENTATION ; PLASTICITY
Indexed BySCI
Language英语
Funding OrganizationSpecial Program of Beijing Municipal Science & Technology Commission(Z161100000216146) ; Science and Technology Development Fund of Macau(044/2015/A2) ; Chinese Academy of Sciences(YZ201671) ; CAS(XDB02060001) ; Institute of Automation, CAS(Y3J2031DZ1) ; National Natural Science Foundation of China(61673381 ; 61201050 ; 61306070 ; 31472001)
WOS Research AreaMathematical & Computational Biology
WOS SubjectMathematical & Computational Biology
WOS IDWOS:000418806400001
Citation statistics
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/21725
Collection类脑智能研究中心_神经计算及脑机交互
Affiliation1.Res Base Beijing Modern Mfg Dev, 100 Pingleyuan, Beijing 100124, Peoples R China
2.Beijing Univ Technol, Sch Management, Data Min Lab, 100 Pingleyuan, Beijing 100124, Peoples R China
3.Chinese Acad Sci, Inst Automat, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
4.Macau Univ Sci & Technol, Fac Informat Technol, Ave Wai Long, Taipa, Macau, Peoples R China
5.Chinese Acad Sci, Inst Neurosci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China
6.Beijing Normal Univ, 19 Waida Jie, Beijing 100875, Peoples R China
7.Chinese Acad Sci, Shanghai Inst Biol Sci, Ctr Excellence Brain Sci & Intelligence Technol, 320 Yue Yang Rd, Shanghai 200031, Peoples R China
8.Univ Chinese Acad Sci, Sch Future Technol, 19A Yuquan Rd, Beijing 100049, Peoples R China
Recommended Citation
GB/T 7714
Xie, Qiwei,Chen, Xi,Deng, Hao,et al. An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images[J]. BIODATA MINING,2017,10(10):40.
APA Xie, Qiwei.,Chen, Xi.,Deng, Hao.,Liu, Danqian.,Sun, Yingyu.,...&Han, Hua.(2017).An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images.BIODATA MINING,10(10),40.
MLA Xie, Qiwei,et al."An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images".BIODATA MINING 10.10(2017):40.
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