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An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images
Xie, Qiwei1,2,3; Chen, Xi3; Deng, Hao4; Liu, Danqian5; Sun, Yingyu6; Zhou, Xiaojuan6; Yang, Yang5,7; Han, Hua3,7,8
2017-12-20
发表期刊BIODATA MINING
卷号10期号:10页码:40
文章类型Article
摘要Background: In the nervous system, the neurons communicate through synapses. The size, morphology, and connectivity of these synapses are significant in determining the functional properties of the neural network. Therefore, they have always been a major focus of neuroscience research. Two-photon laser scanning microscopy allows the visualization of synaptic structures in vivo, leading to many important findings. However, the identification and quantification of structural imaging data currently rely heavily on manual annotation, a method that is both time-consuming and prone to bias.
关键词In Vivo Two-photon imagIng Synapse Bouton Spine Image Enhancement
WOS标题词Science & Technology ; Life Sciences & Biomedicine
DOI10.1186/s13040-017-0161-5
关键词[WOS]DENDRITIC SPINES ; SEGMENTATION ; PLASTICITY
收录类别SCI
语种英语
项目资助者Special Program of Beijing Municipal Science & Technology Commission(Z161100000216146) ; Science and Technology Development Fund of Macau(044/2015/A2) ; Chinese Academy of Sciences(YZ201671) ; CAS(XDB02060001) ; Institute of Automation, CAS(Y3J2031DZ1) ; National Natural Science Foundation of China(61673381 ; 61201050 ; 61306070 ; 31472001)
WOS研究方向Mathematical & Computational Biology
WOS类目Mathematical & Computational Biology
WOS记录号WOS:000418806400001
引用统计
被引频次:1[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/21725
专题类脑智能研究中心_神经计算及脑机交互
作者单位1.Res Base Beijing Modern Mfg Dev, 100 Pingleyuan, Beijing 100124, Peoples R China
2.Beijing Univ Technol, Sch Management, Data Min Lab, 100 Pingleyuan, Beijing 100124, Peoples R China
3.Chinese Acad Sci, Inst Automat, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
4.Macau Univ Sci & Technol, Fac Informat Technol, Ave Wai Long, Taipa, Macau, Peoples R China
5.Chinese Acad Sci, Inst Neurosci, 320 Yue Yang Rd, Shanghai 200031, Peoples R China
6.Beijing Normal Univ, 19 Waida Jie, Beijing 100875, Peoples R China
7.Chinese Acad Sci, Shanghai Inst Biol Sci, Ctr Excellence Brain Sci & Intelligence Technol, 320 Yue Yang Rd, Shanghai 200031, Peoples R China
8.Univ Chinese Acad Sci, Sch Future Technol, 19A Yuquan Rd, Beijing 100049, Peoples R China
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GB/T 7714
Xie, Qiwei,Chen, Xi,Deng, Hao,et al. An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images[J]. BIODATA MINING,2017,10(10):40.
APA Xie, Qiwei.,Chen, Xi.,Deng, Hao.,Liu, Danqian.,Sun, Yingyu.,...&Han, Hua.(2017).An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images.BIODATA MINING,10(10),40.
MLA Xie, Qiwei,et al."An automated pipeline for bouton, spine, and synapse detection of in vivo two-photon images".BIODATA MINING 10.10(2017):40.
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