Knowledge Commons of Institute of Automation,CAS
HMDD v2.0: a database for experimentally supported human microRNA and disease associations | |
Li, Yang1,2; Qiu, Chengxiang3; Tu, Jian2,4; Geng, Bin4; Yang, Jichun4; Jiang, Tianzi3; Cui, Qinghua2,4 | |
发表期刊 | NUCLEIC ACIDS RESEARCH |
2014 | |
卷号 | 42期号:D1页码:D1070-D1074 |
文章类型 | Article |
摘要 | The Human microRNA Disease Database (HMDD; available via the Web site at http://cmbi.bjmu.edu.cn/hmdd and http://202.38.126.151/hmdd/tools/hmdd2.html) is a collection of experimentally supported human microRNA (miRNA) and disease associations. Here, we describe the HMDD v2.0 update that presented several novel options for users to facilitate exploration of the data in the database. In the updated database, miRNA-disease association data were annotated in more details. For example, miRNA-disease association data from genetics, epigenetics, circulating miRNAs and miRNA-target interactions were integrated into the database. In addition, HMDD v2.0 presented more data that were generated based on concepts derived from the miRNA-disease association data, including disease spectrum width of miRNAs and miRNA spectrum width of human diseases. Moreover, we provided users a link to download all the data in the HMDD v2.0 and a link to submit novel data into the database. Meanwhile, we also maintained the old version of HMDD. By keeping data sets up-to-date, HMDD should continue to serve as a valuable resource for investigating the roles of miRNAs in human disease. |
WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
关键词[WOS] | HUMAN CANCERS ; SIMILARITY ; BIOGENESIS ; GENES |
收录类别 | SCI |
语种 | 英语 |
WOS研究方向 | Biochemistry & Molecular Biology |
WOS类目 | Biochemistry & Molecular Biology |
WOS记录号 | WOS:000331139800157 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/3171 |
专题 | 脑图谱与类脑智能实验室_脑网络组研究 |
作者单位 | 1.Peking Univ, Sch Basic Med Sci, Dept Cell Biol, Beijing 100191, Peoples R China 2.Peking Univ, Sch Basic Med Sci, Dept Biomed Informat, Beijing 100191, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 4.Peking Univ, MOE Key Lab Cardiovasc Sci, Beijing 100191, Peoples R China |
推荐引用方式 GB/T 7714 | Li, Yang,Qiu, Chengxiang,Tu, Jian,et al. HMDD v2.0: a database for experimentally supported human microRNA and disease associations[J]. NUCLEIC ACIDS RESEARCH,2014,42(D1):D1070-D1074. |
APA | Li, Yang.,Qiu, Chengxiang.,Tu, Jian.,Geng, Bin.,Yang, Jichun.,...&Cui, Qinghua.(2014).HMDD v2.0: a database for experimentally supported human microRNA and disease associations.NUCLEIC ACIDS RESEARCH,42(D1),D1070-D1074. |
MLA | Li, Yang,et al."HMDD v2.0: a database for experimentally supported human microRNA and disease associations".NUCLEIC ACIDS RESEARCH 42.D1(2014):D1070-D1074. |
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