HMDD v2.0: a database for experimentally supported human microRNA and disease associations

	HMDD v2.0: a database for experimentally supported human microRNA and disease associations
	Li, Yang 1,2; Qiu, Chengxiang3 ; Tu, Jian 2,4; Geng, Bin 4; Yang, Jichun 4; Jiang, Tianzi3 ; Cui, Qinghua 2,4
发表期刊	NUCLEIC ACIDS RESEARCH
	2014
卷号	42 期号:D1 页码:D1070-D1074
文章类型	Article
摘要	The Human microRNA Disease Database (HMDD; available via the Web site at http://cmbi.bjmu.edu.cn/hmdd and http://202.38.126.151/hmdd/tools/hmdd2.html) is a collection of experimentally supported human microRNA (miRNA) and disease associations. Here, we describe the HMDD v2.0 update that presented several novel options for users to facilitate exploration of the data in the database. In the updated database, miRNA-disease association data were annotated in more details. For example, miRNA-disease association data from genetics, epigenetics, circulating miRNAs and miRNA-target interactions were integrated into the database. In addition, HMDD v2.0 presented more data that were generated based on concepts derived from the miRNA-disease association data, including disease spectrum width of miRNAs and miRNA spectrum width of human diseases. Moreover, we provided users a link to download all the data in the HMDD v2.0 and a link to submit novel data into the database. Meanwhile, we also maintained the old version of HMDD. By keeping data sets up-to-date, HMDD should continue to serve as a valuable resource for investigating the roles of miRNAs in human disease.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	HUMAN CANCERS ; SIMILARITY ; BIOGENESIS ; GENES
收录类别	SCI
语种	英语
WOS研究方向	Biochemistry & Molecular Biology
WOS类目	Biochemistry & Molecular Biology
WOS记录号	WOS:000331139800157
引用统计	被引频次：605[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3171
专题	脑图谱与类脑智能实验室_脑网络组研究
作者单位	1.Peking Univ, Sch Basic Med Sci, Dept Cell Biol, Beijing 100191, Peoples R China 2.Peking Univ, Sch Basic Med Sci, Dept Biomed Informat, Beijing 100191, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 4.Peking Univ, MOE Key Lab Cardiovasc Sci, Beijing 100191, Peoples R China
推荐引用方式 GB/T 7714	Li, Yang,Qiu, Chengxiang,Tu, Jian,et al. HMDD v2.0: a database for experimentally supported human microRNA and disease associations[J]. NUCLEIC ACIDS RESEARCH,2014,42(D1):D1070-D1074.
APA	Li, Yang.,Qiu, Chengxiang.,Tu, Jian.,Geng, Bin.,Yang, Jichun.,...&Cui, Qinghua.(2014).HMDD v2.0: a database for experimentally supported human microRNA and disease associations.NUCLEIC ACIDS RESEARCH,42(D1),D1070-D1074.
MLA	Li, Yang,et al."HMDD v2.0: a database for experimentally supported human microRNA and disease associations".NUCLEIC ACIDS RESEARCH 42.D1(2014):D1070-D1074.