Gender consistency and difference in healthy adults revealed by cortical thickness

CASIA OpenIR > 复杂系统管理与控制国家重点实验室 > 影像分析与机器视觉

	Gender consistency and difference in healthy adults revealed by cortical thickness
	Lv, Bin 1; Li, Jing 2; He, Huiguang1 ; Li, Meng 1; Zhao, Mingchang 1; Ai, Likun 3; Yan, Fei 2; Xian, Junfang 2; Wang, Zhenchang 2
发表期刊	NEUROIMAGE
	2010-11-01
卷号	53 期号:2 页码:373-382
文章类型	Article
摘要	Many previous studies have shown that there exists the gender effect on the structural and functional organization in the human brain Although the reported functional differences are generally consistent, the structural differences are controversial among the various studies. In this study, we particularly focused on the gender-related effect in the gray matter (GM) We performed a structural magnetic resonance imaging (MRI) study in 184 healthy adults (90 males and 94 females) with ages ranging from 18 to 70 years Cortical thickness was measured using an automated surface-based method Based on this surface morphological feature of GM, we first compared their regional differences between males and females We then constructed the morphometry-based anatomical networks derived from cortical thickness measurement, while the anatomical connection between two cortical areas depended upon the statistical dependence of their cortical thickness across subjects Subsequently, we applied graph theoretical approaches to investigate the properties of the resultant anatomical networks The results showed that the significant gender-related differences of cortical thickness appeared extensively in the frontal, parietal and occipital lobes. And there were also some between-group differences in the interregional correlation. Additional graph theoretical analysis on the morphological networks revealed both networks exhibited the small-world efficiency and their patterns of topological vulnerability had no statistical differences The findings on the large sample may provide the evidences to study the gender consistency and difference in the human brain structures. (C) 2010 Published by Elsevier Inc.
关键词	Gender Consistency Gender Difference Cortical Thickness Anatomical Correlation
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	AUTOMATED 3-D EXTRACTION ; COMPLEX BRAIN NETWORKS ; SMALL-WORLD ; CEREBRAL-CORTEX ; SEX-DIFFERENCES ; FUNCTIONAL-ORGANIZATION ; MULTIPLE-SCLEROSIS ; MRI DATA ; VOLUME ; SCHIZOPHRENIA
收录类别	SCI
语种	英语
WOS研究方向	Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
WOS类目	Neurosciences ; Neuroimaging ; Radiology, Nuclear Medicine & Medical Imaging
WOS记录号	WOS:000281688000002
引用统计	被引频次：74[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3733
专题	复杂系统管理与控制国家重点实验室_影像分析与机器视觉
作者单位	1.Chinese Acad Sci, Inst Automat, Key Lab Complex Syst & Intelligence Sci, Beijing 100190, Peoples R China 2.Capital Med Univ, Beijing Tongren Hosp, Dept Radiol, Beijing, Peoples R China 3.Capital Med Univ, Beijing Tongren Hosp, Ctr Eye, Beijing, Peoples R China
第一作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Lv, Bin,Li, Jing,He, Huiguang,et al. Gender consistency and difference in healthy adults revealed by cortical thickness[J]. NEUROIMAGE,2010,53(2):373-382.
APA	Lv, Bin.,Li, Jing.,He, Huiguang.,Li, Meng.,Zhao, Mingchang.,...&Wang, Zhenchang.(2010).Gender consistency and difference in healthy adults revealed by cortical thickness.NEUROIMAGE,53(2),373-382.
MLA	Lv, Bin,et al."Gender consistency and difference in healthy adults revealed by cortical thickness".NEUROIMAGE 53.2(2010):373-382.