Age estimation using cortical surface pattern combining thickness with curvatures
Wang, Jieqiong1; Li, Wenjing1; Miao, Wen1; Dai, Dai1; Hua, Jing2; He, Huiguang1
发表期刊MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING
2014-04-01
卷号52期号:4页码:331-341
文章类型Article
摘要Brain development and healthy aging have been proved to follow a specific pattern, which, in turn, can be applied to help doctors diagnose mental diseases. In this paper, we design a cortical surface pattern (CSP) combining the cortical thickness with curvatures, which constructs an accurate human age estimation model with relevance vector regression. We test our model with two public databases. One is the IXI database (360 healthy subjects aging from 20 to 82 years old were selected), and the other is the INDI database (303 subjects aging from 7 to 22 years old were selected). The results show that our model can achieve as small as 4.57 years deviation in the IXI database and 1.38 years deviation in the INDI database. Furthermore, we employ this surface pattern to age groups classification and get a remarkably high accuracy (97.77 %) and a significantly high sensitivity/specificity (97.30/98.10 %). These results suggest that our designed CSP combining thickness with curvatures is stable and sensitive to brain development, and it is much more powerful than voxel-based morphometry used in previous methods for age estimation.
关键词Age Estimation Cortical Surface Pattern Thickness Curvatures
WOS标题词Science & Technology ; Technology ; Life Sciences & Biomedicine
关键词[WOS]HUMAN CEREBRAL-CORTEX ; GEOMETRICALLY ACCURATE ; OLDER-ADULTS ; BRAIN ; MACHINE ; CLASSIFICATION ; SCHIZOPHRENIA ; MATURITY ; IMAGES ; FMRI
收录类别SCI
语种英语
WOS研究方向Computer Science ; Engineering ; Mathematical & Computational Biology ; Medical Informatics
WOS类目Computer Science, Interdisciplinary Applications ; Engineering, Biomedical ; Mathematical & Computational Biology ; Medical Informatics
WOS记录号WOS:000333184200004
引用统计
被引频次:46[WOS]   [WOS记录]     [WOS相关记录]
文献类型期刊论文
条目标识符http://ir.ia.ac.cn/handle/173211/3758
专题复杂系统管理与控制国家重点实验室_影像分析与机器视觉
作者单位1.Chinese Acad Sci, State Key Lab Management & Control Complex Syst, Inst Automat, Key Lab Mol Imaging, Beijing 100190, Peoples R China
2.Wayne State Univ, Dept Comp Sci, Detroit, MI 48202 USA
第一作者单位中国科学院自动化研究所
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Wang, Jieqiong,Li, Wenjing,Miao, Wen,et al. Age estimation using cortical surface pattern combining thickness with curvatures[J]. MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING,2014,52(4):331-341.
APA Wang, Jieqiong,Li, Wenjing,Miao, Wen,Dai, Dai,Hua, Jing,&He, Huiguang.(2014).Age estimation using cortical surface pattern combining thickness with curvatures.MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING,52(4),331-341.
MLA Wang, Jieqiong,et al."Age estimation using cortical surface pattern combining thickness with curvatures".MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING 52.4(2014):331-341.
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