A fast reconstruction algorithm for fluorescence molecular tomography with sparsity regularization

	A fast reconstruction algorithm for fluorescence molecular tomography with sparsity regularization
	Han, Dong 1; Tian, Jie 1; Zhu, Shouping 1; Feng, Jinchao 2; Qin, Chenghu 1; Zhang, Bo 3; Yang, Xin1
发表期刊	OPTICS EXPRESS
	2010-04-12
卷号	18 期号:8 页码:8630-8646
文章类型	Article
摘要	Through the reconstruction of the fluorescent probe distributions, fluorescence molecular tomography (FMT) can three-dimensionally resolve the molecular processes in small animals in vivo. In this paper, we propose an FMT reconstruction algorithm based on the iterated shrinkage method. By incorporating a surrogate function, the original optimization problem can be decoupled, which enables us to use the general sparsity regularization. Due to the sparsity characteristic of the fluorescent sources, the performance of this method can be greatly enhanced, which leads to a fast reconstruction algorithm. Numerical simulations and physical experiments were conducted. Compared to Newton method with Tikhonov regularization, the iterated shrinkage based algorithm can obtain more accurate results, even with very limited measurement data. (C) 2010 Optical Society of America
关键词	Tomography Image Reconstruction Techniques Spectroscopy Fluorescence Luminescence Medical Biological
WOS标题词	Science & Technology ; Physical Sciences
关键词[WOS]	DIFFUSE OPTICAL TOMOGRAPHY ; BIOLUMINESCENCE TOMOGRAPHY ; TISSUE ; LIGHT
收录类别	SCI
语种	英语
WOS研究方向	Optics
WOS类目	Optics
WOS记录号	WOS:000276610300112
引用统计	被引频次：101[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/3901
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Chinese Acad Sci, Inst Automat, Med Image Proc Grp, Beijing 100190, Peoples R China 2.Beijing Univ Technol China, Coll Elect Informat & Control Engn, Beijing, Peoples R China 3.Northeastern Univ, Sino Dutch Biomed & Informat Engn Sch, Shenyang 110004, Peoples R China
第一作者单位	中国科学院自动化研究所
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Han, Dong,Tian, Jie,Zhu, Shouping,et al. A fast reconstruction algorithm for fluorescence molecular tomography with sparsity regularization[J]. OPTICS EXPRESS,2010,18(8):8630-8646.
APA	Han, Dong.,Tian, Jie.,Zhu, Shouping.,Feng, Jinchao.,Qin, Chenghu.,...&Yang, Xin.(2010).A fast reconstruction algorithm for fluorescence molecular tomography with sparsity regularization.OPTICS EXPRESS,18(8),8630-8646.
MLA	Han, Dong,et al."A fast reconstruction algorithm for fluorescence molecular tomography with sparsity regularization".OPTICS EXPRESS 18.8(2010):8630-8646.

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