Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension

	Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension
	Chen, Hongyan 1; Dai, Jianping 1,2; Zhang, Xiaozhe 3; Wang, Kai 1; Huang, Shuhua 4; Cao, Qingtian 4; Wang, Hong 5; Liang, Yuhong 5; Shi, Chuanying 6; Li, Mengyuan 1; Ha, Tingting 1; Ai, Lin 1,2; Li, Shaowu 1,2; Ma, Jun 1; Wei, Wenjuan 7; You, Youbo 7; Liu, Zhenyu7 ; Tian, Jie 7; Bai, Lijun 8
发表期刊	EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
	2013
卷号	2013 期号:2 页码:697-715
文章类型	Article
摘要	The present study attempted to explore modulated hypothalamus-seeded resting brain network underlying the cardiovascular system in primary hypertensive patients after short-term acupuncture treatment. Thirty right-handed patients (14 male) were divided randomly into acupuncture and control groups. The acupuncture group received a continuous five-day acupuncture treatment and undertook three resting-state fMRI scans and 24-hour ambulatory blood pressure monitoring (ABPM) as well as SF-36 questionnaires before, after, and one month after acupuncture treatment. The control group undertook fMRI scans and 24-hour ABPM. For verum acupuncture, average blood pressure (BP) and heart rate (HR) decreased after treatment but showed no statistical differences. There were no significant differences in BP and HR between the acupuncture and control groups. Notably, SF-36 indicated that bodily pain (P = 0.005) decreased and vitality (P = 0.036) increased after acupuncture compared to the baseline. The hypothalamus-related brain network showed increased functional connectivity with the medulla, brainstem, cerebellum, limbic system, thalamus, and frontal lobes. In conclusion, short-term acupuncture did not decrease BP significantly but appeared to improve body pain and vitality. Acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem.
关键词	Uhplc-ms Aromatic Acid Compounds Paeoniflorin
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
关键词[WOS]	STIMULATION ; ELECTROACUPUNCTURE ; TRIAL ; RESPONSES ; NUCLEUS ; FMRI ; RAT
收录类别	SCI
语种	英语
WOS研究方向	Integrative & Complementary Medicine
WOS类目	Integrative & Complementary Medicine
WOS记录号	WOS:000320235800001
引用统计	被引频次：20[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/4050
专题	中国科学院分子影像重点实验室
通讯作者	Tian, Jie
作者单位	1.Capital Med Univ, Beijing Tiantan Hosp, Dept Radiol, Beijing 100050, Peoples R China 2.Beijing Neurosurg Inst, Beijing 100050, Peoples R China 3.Capital Med Univ, Beijing Tiantan Hosp, Dept Pain, Beijing 100050, Peoples R China 4.China North Vehicle Res Inst Workers Hosp, Dept Med, Beijing 100072, Peoples R China 5.Tiantan Community Hlth Serv Ctr, Beijing 100061, Peoples R China 6.Capital Med Univ, Beijing Tiantan Hosp, Ultrason Ctr, Beijing 100050, Peoples R China 7.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 8.Xi An Jiao Tong Univ, Sch Life Sci & Technol, Key Lab Biomed Informat Engn, Minist Educ,Dept Biomed Engn, Xian 710049, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Chen, Hongyan,Dai, Jianping,Zhang, Xiaozhe,et al. Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2013,2013(2):697-715.
APA	Chen, Hongyan.,Dai, Jianping.,Zhang, Xiaozhe.,Wang, Kai.,Huang, Shuhua.,...&Bai, Lijun.(2013).Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2013(2),697-715.
MLA	Chen, Hongyan,et al."Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2013.2(2013):697-715.

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