Knowledge Commons of Institute of Automation,CAS
CellNet: A Lightweight Model towards Accurate LOC-Based High-Speed Cell Detection | |
Long, Xianlei1,2; Ishii, Idaku3; Gu, Qingyi1 | |
发表期刊 | ELECTRONICS |
2022-05-01 | |
卷号 | 11期号:9页码:20 |
摘要 | Label-free cell separation and sorting in a microfluidic system, an essential technique for modern cancer diagnosis, resulted in high-throughput single-cell analysis becoming a reality. However, designing an efficient cell detection model is challenging. Traditional cell detection methods are subject to occlusion boundaries and weak textures, resulting in poor performance. Modern detection models based on convolutional neural networks (CNNs) have achieved promising results at the cost of a large number of both parameters and floating point operations (FLOPs). In this work, we present a lightweight, yet powerful cell detection model named CellNet, which includes two efficient modules, CellConv blocks and the h-swish nonlinearity function. CellConv is proposed as an effective feature extractor as a substitute to computationally expensive convolutional layers, whereas the h-swish function is introduced to increase the nonlinearity of the compact model. To boost the prediction and localization ability of the detection model, we re-designed the model's multi-task loss function. In comparison with other efficient object detection methods, our approach achieved state-of-the-art 98.70% mean average precision (mAP) on our custom sea urchin embryos dataset with only 0.08 M parameters and 0.10 B FLOPs, reducing the size of the model by 39.5 x and the computational cost by 4.6 x. We deployed CellNet on different platforms to verify its efficiency. The inference speed on a graphics processing unit (GPU) was 500.0 fps compared with 87.7 fps on a CPU. Additionally, CellNet is 769.5-times smaller and 420 fps faster than YOLOv3. Extensive experimental results demonstrate that CellNet can achieve an excellent efficiency/accuracy trade-off on resource-constrained platforms. |
其他摘要 |
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关键词 | cell detection high-speed vision convolutional neural network (CNN) efficient convolutional block medical image analysis |
DOI | 10.3390/electronics11091407 |
关键词[WOS] | CLASSIFICATION ; AUTOENCODER ; EFFICIENT ; NUCLEI |
收录类别 | SCI |
语种 | 英语 |
资助项目 | Scientific Instrument Developing Project of the Chinese Academy of Sciences[YJKYYQ20200045] |
项目资助者 | Scientific Instrument Developing Project of the Chinese Academy of Sciences |
WOS研究方向 | Computer Science ; Engineering ; Physics |
WOS类目 | Computer Science, Information Systems ; Engineering, Electrical & Electronic ; Physics, Applied |
WOS记录号 | WOS:000794685000001 |
出版者 | MDPI |
七大方向——子方向分类 | 其他 |
国重实验室规划方向分类 | 其他 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.ia.ac.cn/handle/173211/49381 |
专题 | 中科院工业视觉智能装备工程实验室_精密感知与控制 中国科学院自动化研究所 |
通讯作者 | Gu, Qingyi |
作者单位 | 1.Chinese Acad Sci, Inst Automat, Res Ctr Precis Sensing & Control, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 100049, Peoples R China 3.Hiroshima Univ, Grad Sch Adv Sci & Engn, Smart Robot Lab, Hiroshima 7398527, Japan |
第一作者单位 | 精密感知与控制研究中心 |
通讯作者单位 | 精密感知与控制研究中心 |
推荐引用方式 GB/T 7714 | Long, Xianlei,Ishii, Idaku,Gu, Qingyi. CellNet: A Lightweight Model towards Accurate LOC-Based High-Speed Cell Detection[J]. ELECTRONICS,2022,11(9):20. |
APA | Long, Xianlei,Ishii, Idaku,&Gu, Qingyi.(2022).CellNet: A Lightweight Model towards Accurate LOC-Based High-Speed Cell Detection.ELECTRONICS,11(9),20. |
MLA | Long, Xianlei,et al."CellNet: A Lightweight Model towards Accurate LOC-Based High-Speed Cell Detection".ELECTRONICS 11.9(2022):20. |
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