CASIA OpenIR  > 中国科学院分子影像重点实验室
A Streamlined 3-D Magnetic Particle Imaging System With a Two-Stage Excitation Feed-Through Compensation Strategy
Yin L(尹琳); Li W(李玮); Bian ZW(卞忠伟); Chen ZW(陈梓威); Liu YJ(刘晏君); Zhong J(钟景); Zhang SX(张水兴); Du Y(杜洋); Hui H(惠辉); Tian J(田捷)
Source PublicationIEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
ISSN0018-9456
2023
Volume72Pages:1-10
Corresponding AuthorZhang, Shuixing(shui7515@126.com) ; Du, Yang(yang.du@ia.ac.cn) ; Hui, Hui(hui.hui@ia.ac.cn) ; Tian, Jie(tian@ieee.org)
SubtypeSCI
Abstract

Magnetic particle imaging (MPI) is an innovative
molecular imaging technique with remarkable sensitivity and
temporal–spatial resolution. It employs superparamagnetic iron
oxide nanoparticles (SPIONs) as tracers to precisely locate lesions
in quantitative imaging. In practical, the induced signal of the
receiver coil contains both the SPIONs magnetization signal and
the excitation feed-through signal. Due to the high amplitude of
the latter, extracting the SPIONs signal from the induced signal
is a challenging task. In this study, a two-stage compensation
strategy was proposed to suppress excitation feed-through signal.
Firstly, we used a three-stage gradiometer coil to suppress
part of the feed-through signal. Secondly, different from using
the band-stop filters in most previous studies, we proposed
a modulation compensation strategy that the received signal
from the first stage and a modulation signal were input to the
differential circuit at the same time, and the feed-through signal
can be suppressed by actively adjusting the modulation signal.
In addition, we presented a 3-D MPI system with a simple and
effective structure. Permanent magnets were used to generate
gradient fields, and the two-stage compensation strategy was
employed at the receiving chain. Experimental results showed
that the proposed compensation strategy can obviously suppress
the excitation feed-through signal, which allows to achieve a high resolution and sensitivity imaging with the proposed 3-D MPI
system.

Keyword3-D imaging compensation strategy magnetic particle imaging (MPI)
DOI10.1109/TIM.2023.3328682
WOS KeywordNANOPARTICLE ; TRACER
Indexed BySCI
Language英语
Funding ProjectNational Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81227901] ; National Natural Science Foundation of China[81930053] ; National Natural Science Foundation of China[62201570] ; National Natural Science Foundation of China[82230067] ; Beijing Natural Science Foundation[JQ22023] ; Guangdong Basic and Applied Basic Research Foundation[2022A1515110798] ; Project of High-Level Talents Team Introduction in Zhuhai City[HLHPTP201703]
Funding OrganizationNational Natural Science Foundation of China ; Beijing Natural Science Foundation ; Guangdong Basic and Applied Basic Research Foundation ; Project of High-Level Talents Team Introduction in Zhuhai City
WOS Research AreaEngineering ; Instruments & Instrumentation
WOS SubjectEngineering, Electrical & Electronic ; Instruments & Instrumentation
WOS IDWOS:001137576400017
PublisherIEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
Sub direction classification医学影像处理与分析
planning direction of the national heavy laboratoryAI For Science
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Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/55385
Collection中国科学院分子影像重点实验室
Recommended Citation
GB/T 7714
Yin L,Li W,Bian ZW,et al. A Streamlined 3-D Magnetic Particle Imaging System With a Two-Stage Excitation Feed-Through Compensation Strategy[J]. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,2023,72:1-10.
APA Yin L.,Li W.,Bian ZW.,Chen ZW.,Liu YJ.,...&Tian J.(2023).A Streamlined 3-D Magnetic Particle Imaging System With a Two-Stage Excitation Feed-Through Compensation Strategy.IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,72,1-10.
MLA Yin L,et al."A Streamlined 3-D Magnetic Particle Imaging System With a Two-Stage Excitation Feed-Through Compensation Strategy".IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT 72(2023):1-10.
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