CASIA OpenIR  > 中国科学院分子影像重点实验室
Weighted sum of harmonic signals for direct imaging in magnetic particle imaging
Liu, Yanjun1,2,3,4,5; Hui, Hui4,5,6; Liu, Sijia4,5,7; Li, Guanghui1,2,3,4,5; Zhang, Bo1,2,3,4,5; Zhong, Jing8; An, Yu1,2,3,4,5; Tian, Jie1,2,3,4,5,7,9
Source PublicationPHYSICS IN MEDICINE AND BIOLOGY
ISSN0031-9155
2023-07-01
Volume68Issue:1Pages:13
Corresponding AuthorHui, Hui(hui.hui@ia.ac.cn) ; Tian, Jie(tian@ieee.org)
AbstractObjective. Magnetic particle imaging (MPI) is a novel radiation-free medical imaging modality that can directly image superparamagnetic iron oxide tracers (SPIOs) with high sensitivity, temporal resolution, and good spatial resolution. The MPI reconstruction task can be formulated mathematically as a Fredholm integral problem, but the concrete inversion is not easily possible because of the particle dynamics or scanner issues. Measurement based system matrix inversion takes these factors into account, but prior measurement and calibration are time consuming. Approach. We proposed a direct imaging method based on the weighted sum of harmonic signals. The harmonic signals with spatial information are obtained by the short-time Fourier transform, and odd harmonic components are selected for recombination and then mapped to the sampling trajectory to image the concentration distribution of SPIOs. In addition, we adopt a normalized-weighted sum of harmonics to improve the resolution of the native image. Main results. The effectiveness of the proposed method is verified by simulation imaging experiments and our in-house scanner-based experiments. Quantitative evaluation results show that compared with traditional methods, the structural similarity improved by 48%, mean square error decreased by 88%, and signal-to-artifact ratio increased by 2.5 times. Significance. The proposed method can rapidly image the concentration distribution of nanoparticles without any prior calibration measurements and reduce the blur of MPI images without deconvolution, which has the potential to be implemented as a multi-patch imaging method in MPI.
Keywordmagnetic particle imaging short-time fourier transform direct imaging multi-patch imaging
DOI10.1088/1361-6560/aca9b9
WOS KeywordRECONSTRUCTION ; NANOPARTICLE ; PERFORMANCE ; AMPLITUDE ; TRACER ; MOTION
Indexed BySCI
Language英语
Funding ProjectNational Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[81930053] ; National Natural Science Foundation of China[81227901] ; CAS Youth Innovation Promotion Association[2018167] ; CAS Key Technology Talent Program ; Guangdong Key Research and Development Program of China[2021B0101420005] ; Project of High-Level Talents Team Introduction in Zhuhai City[Zhuhai HLHPTP201703]
Funding OrganizationNational Key Research and Development Program of China ; National Natural Science Foundation of China ; CAS Youth Innovation Promotion Association ; CAS Key Technology Talent Program ; Guangdong Key Research and Development Program of China ; Project of High-Level Talents Team Introduction in Zhuhai City
WOS Research AreaEngineering ; Radiology, Nuclear Medicine & Medical Imaging
WOS SubjectEngineering, Biomedical ; Radiology, Nuclear Medicine & Medical Imaging
WOS IDWOS:000904747700001
PublisherIOP Publishing Ltd
Citation statistics
Cited Times:8[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.ia.ac.cn/handle/173211/51082
Collection中国科学院分子影像重点实验室
Corresponding AuthorHui, Hui; Tian, Jie
Affiliation1.Beihang Univ, Sch Engn Med, Beijing 100191, Peoples R China
2.Beihang Univ, Sch Biol Sci & Med Engn, Beijing 100191, Peoples R China
3.Beihang Univ, Key Lab Big Data Based Precis Med, Minist Ind & Informat Technol Peoples Republ China, Beijing 100191, Peoples R China
4.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
5.Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China
6.Univ Chinese Acad Sci, Beijing, Peoples R China
7.Southeast Univ, Sch Comp Sci & Engn, Nanjing 210096, Peoples R China
8.Beihang Univ, Sch Instrumentat & Optoelect Engn, Beijing 100191, Peoples R China
9.Jinan Univ, Zhuhai Peoples Hosp, Zhuhai Precis Med Ctr, Zhuhai 519000, Peoples R China
First Author AffilicationChinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
Corresponding Author AffilicationChinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China
Recommended Citation
GB/T 7714
Liu, Yanjun,Hui, Hui,Liu, Sijia,et al. Weighted sum of harmonic signals for direct imaging in magnetic particle imaging[J]. PHYSICS IN MEDICINE AND BIOLOGY,2023,68(1):13.
APA Liu, Yanjun.,Hui, Hui.,Liu, Sijia.,Li, Guanghui.,Zhang, Bo.,...&Tian, Jie.(2023).Weighted sum of harmonic signals for direct imaging in magnetic particle imaging.PHYSICS IN MEDICINE AND BIOLOGY,68(1),13.
MLA Liu, Yanjun,et al."Weighted sum of harmonic signals for direct imaging in magnetic particle imaging".PHYSICS IN MEDICINE AND BIOLOGY 68.1(2023):13.
Files in This Item:
There are no files associated with this item.
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Liu, Yanjun]'s Articles
[Hui, Hui]'s Articles
[Liu, Sijia]'s Articles
Baidu academic
Similar articles in Baidu academic
[Liu, Yanjun]'s Articles
[Hui, Hui]'s Articles
[Liu, Sijia]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Liu, Yanjun]'s Articles
[Hui, Hui]'s Articles
[Liu, Sijia]'s Articles
Terms of Use
No data!
Social Bookmark/Share
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.