Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer

doi:10.1109/TIM.2023.3298428

	Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer
	Zhang, Haoran 1,2; Zhang, Bo 1,2; Feng, Xin3,4 ; Zhang, Yingqian 5,6; Chen, Yundai 5,6; Hui, Hui3,4 ; Tian, Jie 1,2
发表期刊	IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
ISSN	0018-9456
	2023
卷号	72 页码:10
通讯作者	Hui, Hui(hui.hui@ia.ac.cn) ; Tian, Jie(tian@ieee.org)
摘要	Magnetic particle spectrometer (MPS) is the device for characterizing the properties of magnetic nanoparticle (MNP) suspensions, such as viscosity, temperature, and concentration. Specifically, in viscosity measurement, MPS usually works at one or several fixed frequencies. It is challenging to find the appropriate frequency for viscosity measurement of different MNP suspensions. The frequency parameter can be introduced into the measurement method to improve the measurement accuracy. Here, we developed an arbitrary frequency MPS to measure the harmonic amplitudes of the magnetization signals of MNPs, which were generated at various frequencies. A method of measuring the viscosity of MNP suspensions by harmonic ratios at different frequencies was proposed. The viscosity measurement time used in the experiment is 1 s, and the shortest measurement time available is 0.2 s. Experimental results show that the arbitrary frequency MPS can measure the viscosity of samples ranging from 0.77 mPa.s to 3.87 mPa.s, and the average measurement deviation is 2.7%. The method was validated using plasma samples from normal rabbits and high-fat diet (HFD) rabbits. Normal rabbit measurements differed from the reference by less than 4.5%, and the plasma viscosity of normal and HFD rabbits could be clearly distinguished.
关键词	Arbitrary frequency magnetic nanoparticles (MNPs) magnetic particle spectrometer (MPS) viscosity measurement
DOI	10.1109/TIM.2023.3298428
关键词[WOS]	WHOLE-BLOOD VISCOSITY ; PLASMA
收录类别	SCI
语种	英语
资助项目	National Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[81827808] ; National Natural Science Foundation of China[81227901] ; Beijing Natural Science Foundation[JQ22023] ; Beijing Natural Science Foundation[7232346] ; Chinese Academy of Sciences Youth Innovation Promotion Association[Y2022055] ; Key Technology Talent Program
项目资助者	National Key Research and Development Program of China ; National Natural Science Foundation of China ; Beijing Natural Science Foundation ; Chinese Academy of Sciences Youth Innovation Promotion Association ; Key Technology Talent Program
WOS研究方向	Engineering ; Instruments & Instrumentation
WOS类目	Engineering, Electrical & Electronic ; Instruments & Instrumentation
WOS记录号	WOS:001045579100022
出版者	IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
引用统计
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/54063
专题	中国科学院分子影像重点实验室
通讯作者	Hui, Hui; Tian, Jie
作者单位	1.Beihang Univ, Sch Engn Med, Sch Biol Sci & Med Engn, Beijing 100191, Peoples R China 2.Beihang Univ, Key Lab Big DataBased Precis Med, Minist Ind & Informat Technol China, Beijing 100191, Peoples R China 3.Chinese Acad Sci, Inst Automat, CAS Key Lab Mol Imaging, Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100190, Peoples R China 5.Sr Dept Cardiol, Beijing 100048, Peoples R China 6.Sixth Med Ctr PLA Gen Hosp, Beijing 100048, Peoples R China
通讯作者单位	中国科学院分子影像重点实验室
推荐引用方式 GB/T 7714	Zhang, Haoran,Zhang, Bo,Feng, Xin,et al. Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer[J]. IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,2023,72:10.
APA	Zhang, Haoran.,Zhang, Bo.,Feng, Xin.,Zhang, Yingqian.,Chen, Yundai.,...&Tian, Jie.(2023).Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer.IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT,72,10.
MLA	Zhang, Haoran,et al."Rapid Viscosity Measurement Using Arbitrary Frequency Magnetic Particle Spectrometer".IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT 72(2023):10.