Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan

doi:10.3390/bioengineering9100524

	Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan
	Yang, Qi 1,2; Han, Jiancheng 1,2; Wang, Rui 1,2; Zhang, Tong 3; Zhang, Yingying1,2 ; Wang, Jingyi 1,2; Xu, Lei 1,2; Hou, Zengguang4 ; Wang, Shuangyi4 ; He, Yihua 1,2
发表期刊	BIOENGINEERING-BASEL
	2022-10-01
卷号	9 期号:10 页码:9
通讯作者	Wang, Shuangyi(shuangyi.wang@ia.ac.cn) ; He, Yihua(heyihuaecho@hotmail.com)
摘要	Despite recent breakthroughs in diagnosis and treatment, congenital heart defects (CHDs) continue to be the leading cause of death among newborns. Fetal echocardiography is the most effective and non-invasive method for the prenatal diagnosis of CHDs. However, the challenge of obtaining standard views can lead to a low diagnostic accuracy. To explore new methods for training, the combined use of cardiovascular casting, computed tomography (CT) scanning, and virtual ultrasound generation methods was studied to preserve the cardiac structures of a fetus in digital form. The feasibility of the proposed workflow was verified by testing three fetal heart specimens collected after the termination of pregnancy. As a result, the anatomical structures were imaged clearly by a CT scan after cardiovascular casting, and the virtually generated ultrasound images based on the use of the Public software Library for UltraSound imaging research (PLUS) toolkit successfully demonstrated both the standard views and the views with diagnostic values for the visualization of the cardiovascular structures. This solution provides great data extensibility while being simple and cost-effective for end users. Therefore, the proposed method could provide a promising educational system for trainees to understand standard views of fetal echocardiography and the corresponding anatomical correlations.
关键词	congenital heart disease fetal echocardiography digital twin cardiovascular casting virtual ultrasound
DOI	10.3390/bioengineering9100524
收录类别	SCI
语种	英语
资助项目	National Natural Science Foundation of China[U21A20523] ; National Natural Science Foundation of China[62003339]
项目资助者	National Natural Science Foundation of China
WOS研究方向	Biotechnology & Applied Microbiology ; Engineering
WOS类目	Biotechnology & Applied Microbiology ; Engineering, Biomedical
WOS记录号	WOS:000872284800001
出版者	MDPI
引用统计	被引频次：1[WOS] [WOS记录] [WOS相关记录]
文献类型	期刊论文
条目标识符	http://ir.ia.ac.cn/handle/173211/50527
专题	复杂系统认知与决策实验室_先进机器人
通讯作者	Wang, Shuangyi; He, Yihua
作者单位	1.Capital Med Univ, Beijing Anzhen Hosp, Echocardiog Med Ctr, Beijing 100029, Peoples R China 2.Beijing Anzhen Hosp, Maternal Fetal Med Ctr Fetal Heart Dis, Beijing 100029, Peoples R China 3.Peng Cheng Lab PCL, Dept Network Intelligence, Shenzhen 518055, Peoples R China 4.Chinese Acad Sci, Inst Automat, State Key Lab Management & Control Complex Syst, Beijing 100190, Peoples R China
通讯作者单位	中国科学院自动化研究所
推荐引用方式 GB/T 7714	Yang, Qi,Han, Jiancheng,Wang, Rui,et al. Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan[J]. BIOENGINEERING-BASEL,2022,9(10):9.
APA	Yang, Qi.,Han, Jiancheng.,Wang, Rui.,Zhang, Tong.,Zhang, Yingying.,...&He, Yihua.(2022).Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan.BIOENGINEERING-BASEL,9(10),9.
MLA	Yang, Qi,et al."Development of Digital Fetal Heart Models with Virtual Ultrasound Function Based on Cardiovascular Casting and Computed Tomography Scan".BIOENGINEERING-BASEL 9.10(2022):9.