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A neuroimaging biomarker for Individual Brain-Related Abnormalities In Neurodegeneration (IBRAIN): a cross-sectional study 期刊论文
ECLINICALMEDICINE, 2023, 卷号: 65, 页码: 14
作者:  Zhao, Kun;  Chen, Pindong;  Alexander-Bloch, Aaron;  Wei, Yongbin;  Dyrba, Martin;  Yang, Fan;  Kang, Xiaopeng;  Wang, Dawei;  Fan, Dongsheng;  Ye, Shan;  Tang, Yi;  Yao, Hongxiang;  Zhou, Bo;  Lu, Jie;  Yu, Chunshui;  Wang, Pan;  Liao, Zhengluan;  Chen, Yan;  Huang, Longjian;  Zhang, Xi;  Han, Ying;  Li, Shuyu;  Liu, Yong
收藏  |  浏览/下载：31/0  |  提交时间：2024/02/22
Alzheimer's disease  Neuroimaging biomarker  Multisite  Specific  Longitudinal progression  
An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography 期刊论文
BMC BIOLOGY, 2023, 卷号: 21, 期号: 1, 页码: 14
作者:  Chang, Sheng;  Li, Linlin;  Hong, Bei;  Liu, Jing;  Xu, Yuxuan;  Pang, Keliang;  Zhang, Lina;  Han, Hua;  Chen, Xi
收藏  |  浏览/下载：84/0  |  提交时间：2023/11/16
Serial section electron tomography  3D EM  Semi-auto locating  Auto-alignment  Missing-information restoration  Semi-auto segmentation  Workflow  Synapse  
A novel registration method for long-serial section images of EM with a serial split technique based on unsupervised optical flow network 期刊论文
BIOINFORMATICS, 2023, 卷号: 39, 期号: 8, 页码: 11
作者:  Xin, Tong;  Lv, Yanan;  Chen, Haoran;  Li, Linlin;  Shen, Lijun;  Shan, Guangcun;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载：109/0  |  提交时间：2023/11/17
Four Distinct Subtypes of Alzheimer?s Disease Based on Resting-State Connectivity Biomarkers 期刊论文
BIOLOGICAL PSYCHIATRY, 2023, 卷号: 93, 期号: 9, 页码: 759-769
作者:  Chen, Pindong;  Yao, Hongxiang;  Tijms, Betty M.;  Wang, Pan;  Wang, Dawei;  Song, Chengyuan;  Yang, Hongwei;  Zhang, Zengqiang;  Zhao, Kun;  Qu, Yida;  Kang, Xiaopeng;  Du, Kai;  Fan, Lingzhong;  Han, Tong;  Yu, Chunshui;  Zhang, Xi;  Jiang, Tianzi;  Zhou, Yuying;  Lu, Jie;  Han, Ying;  Liu, Bing;  Zhou, Bo;  Liu, Yong
收藏  |  浏览/下载：143/0  |  提交时间：2023/11/17
Joint reconstruction of neuron and ultrastructure via connectivity consensus in electron microscope volumes 期刊论文
BMC Bioinformatics, 2022, 卷号: 23, 期号: 1, 页码: 23
作者:  Hong,Bei;  Liu,Jing;  Zhai,Hao;  Liu,Jiazheng;  Shen,Lijun;  Chen,Xi;  Xie,Qiwei;  Han,Hua
Adobe PDF(3091Kb)  |  收藏  |  浏览/下载：313/78  |  提交时间：2022/11/14
Connectomics  Reconstruction  Connectivity concept  Joint optimization  Electron microscope volumes  
Fusion and expansion of vitellogenin vesicles during Caenorhabditis elegans intestinal senescence 期刊论文
AGING CELL, 2022, 页码: 13
作者:  Zhai, Chao;  Zhang, Nan;  Li, Xi-Xia;  Chen, Xi;  Sun, Fei;  Dong, Meng-Qiu
收藏  |  浏览/下载：184/0  |  提交时间：2022/11/14
Aging  C  elegans  Senescence  Vesicle fusion  Vitellogenin  Yolk  
Expected affine: A registration method for damaged section in serial sections electron microscopy 期刊论文
FRONTIERS IN NEUROINFORMATICS, 2022, 卷号: 16, 页码: 11
作者:  Xin, Tong;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
收藏  |  浏览/下载：205/0  |  提交时间：2022/11/14
image registration  SSEM  broken sections  section fold  section crack  
Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data 期刊论文
CELL REPORTS, 2022, 卷号: 40, 期号: 5, 页码: 28
作者:  Liu, Jing;  Qi, Junqian;  Chen, Xi;  Li, Zhenchen;  Hong, Bei;  Ma, Hongtu;  Li, Guoqing;  Shen, Lijun;  Liu, Danqian;  Kong, Yu;  Zhai, Hao;  Xie, Qiwei;  Han, Hua;  Yang, Yang
收藏  |  浏览/下载：278/0  |  提交时间：2022/09/19
Denoising of scanning electron microscope images for biological ultrastructure enhancement 期刊论文
JOURNAL OF BIOINFORMATICS AND COMPUTATIONAL BIOLOGY, 2022, 卷号: 20, 期号: 03, 页码: 21
作者:  Chang, Sheng;  Shen, Lijun;  Li, Linlin;  Chen, Xi;  Han, Hua
Adobe PDF(4726Kb)  |  收藏  |  浏览/下载：278/37  |  提交时间：2022/09/19
SEM  noise model  denoising  variance stabilization transformation  two-stage multi-loss  deep learning  
Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy 期刊论文
Journal of Molecular Cell Biology, 2022, 页码: 已录用
作者:  Yi Jiang;  Linlin Li;  Keliang Pang;  Jiazheng Liu;  Bohao Chen;  Jingbin Yuan;  Lijun Shen;  Xi Chen;  Bai Lu;  Hua Han
Adobe PDF(689Kb)  |  收藏  |  浏览/下载：387/160  |  提交时间：2022/07/01