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Synergy evaluation by a pathway-pathway interaction network: a new way to predict drug combination 期刊论文
MOLECULAR BIOSYSTEMS, 2016, 卷号: 12, 期号: 2, 页码: 614-623
作者:  Chen, Di;  Zhang, Huamin;  Lu, Peng;  Liu, Xianli;  Cao, Hongxin;  Cao Hongxin
浏览  |  Adobe PDF(2974Kb)  |  收藏  |  浏览/下载：270/57  |  提交时间：2016/06/14
Drug Synergy  Pathway Interaction  
NEW DRUG R&D OF TRADITIONAL CHINESE MEDICINE: ROLE OF DATA MINING APPROACHES 期刊论文
JOURNAL OF BIOLOGICAL SYSTEMS, 2009, 卷号: 17, 期号: 3, 页码: 329-347
作者:  Yang, Hongjun;  Chen, Jianxin;  Tang, Shihuan;  Li, Zhenkun;  Zhen, Yisong;  Huang, Luqi;  Yi, Jianqiang
浏览  |  Adobe PDF(293Kb)  |  收藏  |  浏览/下载：427/90  |  提交时间：2015/11/08
Drug Discovery  Traditional Chinese Medicine  Data Mining  Unsupervised Cluster  Supervised Regression  Formulae  Association  Mutual Information  
Systematic synergy modeling: understanding drug synergy from a systems biology perspective 期刊论文
BMC SYSTEMS BIOLOGY, 2015, 卷号: 9, 期号: 2015, 页码: 56
作者:  Chen, Di;  Liu, Xi;  Yang, Yiping;  Yang, Hongjun;  Lu, Peng;  Lu,Peng
浏览  |  Adobe PDF(1011Kb)  |  收藏  |  浏览/下载：337/42  |  提交时间：2015/11/04
Drug Synergy  Systematic Modeling  
An effective solution to discover synergistic drugs for anti-cerebral ischemia from traditional Chinese medicinal formulae 期刊论文
ACTA PHARMACOLOGICA SINICA, 2013, 卷号: 34, 期号: 11, 页码: 116-117
作者:  Wu, Chuan-hong;  Chen, Jian-xin;  Lu, Pang;  Chen, Chang;  Li, Shao-jing
收藏  |  浏览/下载：241/0  |  提交时间：2015/09/23
Matrix Factorization-Based Prediction of Novel Drug Indications by Integrating Genomic Space 期刊论文
COMPUTATIONAL AND MATHEMATICAL METHODS IN MEDICINE, 2015, 卷号: 2015, 期号: 2015, 页码: 275045
作者:  Dai, Wen;  Liu, Xi;  Gao, Yibo;  Chen, Lin;  Song, Jianglong;  Chen, Di;  Gao, Kuo;  Jiang, Yongshi;  Yang, Yiping;  Chen, Jianxin;  Lu, Peng
浏览  |  Adobe PDF(1467Kb)  |  收藏  |  浏览/下载：403/87  |  提交时间：2015/09/17
Matrix Factorization  Drug Indication  Genomic Space  
Pathway Pattern-based prediction of active drug components and gene targets from H1N1 influenza's treatment with maxingshigan-yinqiaosan formula 期刊论文
MOLECULAR BIOSYSTEMS, 2013, 卷号: 9, 期号: 3, 页码: 375-385
作者:  Dai, Wen;  Chen, Jianxin;  Lu, Peng;  Gao, Yibo;  Chen, Lin;  Liu, Xi;  Song, Jianglong;  Xu, Haiyu;  Chen, Di;  Yang, Yiping;  Yang, Hongjun;  Huang, Luqi
浏览  |  Adobe PDF(742Kb)  |  收藏  |  浏览/下载：339/36  |  提交时间：2015/08/12
In Silico Syndrome Prediction for Coronary Artery Disease in Traditional Chinese Medicine 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2012
作者:  Lu, Peng;  Chen, Jianxin;  Zhao, Huihui;  Gao, Yibo;  Luo, Liangtao;  Zuo, Xiaohan;  Shi, Qi;  Yang, Yiping;  Yi, Jianqiang;  Wang, Wei
Adobe PDF(1009Kb)  |  收藏  |  浏览/下载：323/83  |  提交时间：2015/08/12
A Network-Based Systematic Study for the Mechanism of the Treatment of Zhengs Related to Cough Variant Asthma 期刊论文
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2013, 卷号: 2013, 期号: 2013, 页码: 595924
作者:  Chen, Di;  Zhang, Fangbo;  Tang, Shihuan;  Chen, Yan;  Lu, Peng;  Wen, Shaoxin;  Zhang, Hongchun;  Liu, Xi;  Chao, Enxiang;  Yang, Hongjun
浏览  |  Adobe PDF(5666Kb)  |  收藏  |  浏览/下载：272/59  |  提交时间：2015/08/12
Systematic Study  Zheng Mechanism  Cough Variant Asthma  
A new strategy in drug design of chinese medicine: Theory, method and techniques 期刊论文
CHINESE JOURNAL OF INTEGRATIVE MEDICINE, 2012, 卷号: 18, 期号: 11, 页码: 803-806
作者:  Yang Hong-jun;  Shen Dan;  Xu Hai-yu;  Lu Peng
收藏  |  浏览/下载：145/0  |  提交时间：2015/08/12
Drug Design Of Chinese Medicine  Combination-activity Relationship  Prescription Discovery  Component Identification  Formula Optimization  System Modeling  
BUILDING AND EVALUATING AN ANIMAL MODEL FOR SYNDROME IN TRADITIONAL CHINESE MEDICINE IN THE CONTEXT OF UNSTABLE ANGINA (MYOCARDIAL ISCHEMIA) BY SUPERVISED DATA MINING APPROACHES 期刊论文
JOURNAL OF BIOLOGICAL SYSTEMS, 2009, 卷号: 17, 期号: 4, 页码: 531-546
作者:  Guo, Shuzhen;  Chen, Jianxin;  Zhao, Huihui;  Wang, Wei;  Yi, Jianqiang;  Liu, Lei;  Qi, Qige;  Liu, Renquan;  Qiu, Qi;  Wang, Yong
Adobe PDF(494Kb)  |  收藏  |  浏览/下载：270/71  |  提交时间：2015/08/12
Unstable Angina  Blood Stasis Syndrome  Traditional Chinese Medicine  Data Mining  Animal Model  Myocardial Ischemia  Classification  Radial Basis Function Network