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An intelligent workflow for sub-nanoscale 3D reconstruction of intact synapses from serial section electron tomography 期刊论文
BMC BIOLOGY, 2023, 卷号: 21, 期号: 1, 页码: 14
作者:  Chang, Sheng;  Li, Linlin;  Hong, Bei;  Liu, Jing;  Xu, Yuxuan;  Pang, Keliang;  Zhang, Lina;  Han, Hua;  Chen, Xi
收藏  |  浏览/下载：78/0  |  提交时间：2023/11/16
Serial section electron tomography  3D EM  Semi-auto locating  Auto-alignment  Missing-information restoration  Semi-auto segmentation  Workflow  Synapse  
Joint reconstruction of neuron and ultrastructure via connectivity consensus in electron microscope volumes 期刊论文
BMC Bioinformatics, 2022, 卷号: 23, 期号: 1, 页码: 23
作者:  Hong,Bei;  Liu,Jing;  Zhai,Hao;  Liu,Jiazheng;  Shen,Lijun;  Chen,Xi;  Xie,Qiwei;  Han,Hua
Adobe PDF(3091Kb)  |  收藏  |  浏览/下载：298/75  |  提交时间：2022/11/14
Connectomics  Reconstruction  Connectivity concept  Joint optimization  Electron microscope volumes  
Fear memory-associated synaptic and mitochondrial changes revealed by deep learning-based processing of electron microscopy data 期刊论文
CELL REPORTS, 2022, 卷号: 40, 期号: 5, 页码: 28
作者:  Liu, Jing;  Qi, Junqian;  Chen, Xi;  Li, Zhenchen;  Hong, Bei;  Ma, Hongtu;  Li, Guoqing;  Shen, Lijun;  Liu, Danqian;  Kong, Yu;  Zhai, Hao;  Xie, Qiwei;  Han, Hua;  Yang, Yang
收藏  |  浏览/下载：265/0  |  提交时间：2022/09/19
Synaptic degeneration in the prefrontal cortex of a rat AD model revealed by volume electron microscopy 期刊论文
Journal of Molecular Cell Biology, 2022, 页码: 已录用
作者:  Yi Jiang;  Linlin Li;  Keliang Pang;  Jiazheng Liu;  Bohao Chen;  Jingbin Yuan;  Lijun Shen;  Xi Chen;  Bai Lu;  Hua Han
Adobe PDF(689Kb)  |  收藏  |  浏览/下载：374/156  |  提交时间：2022/07/01
Diffusion tensor imaging of the hippocampus reflects the severity of hippocampal injury induced by global cerebral ischemia/reperfusion injury 期刊论文
NEURAL REGENERATION RESEARCH, 2022, 卷号: 17, 期号: 4, 页码: 838-844
作者:  Wang, Wen-Zhu;  Liu, Xu;  Yang, Zheng-Yi;  Wang, Yi-Zheng;  Lu, Hai-Tao
收藏  |  浏览/下载：202/0  |  提交时间：2022/06/06
brain-derived neurotrophic factor  diffusion tensor imaging  fractional anisotropy value  global cerebral ischemia/reperfusion injury  hippocampus  TrkB  
Three-dimensional ATUM-SEM reconstruction and analysis of hepatic endoplasmic reticulum-organelle interactions 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 9, 页码: 636-645
作者:  Jiang, Yi;  Li, Linlin;  Chen, Xi;  Liu, Jiazheng;  Yuan, Jingbin;  Xie, Qiwei;  Han, Hua
Adobe PDF(1914Kb)  |  收藏  |  浏览/下载：300/41  |  提交时间：2022/01/27
3D reconstruction  ATUM-SEM  deep learning  liver  ER  MCSs  
An effective AI integrated system for neuron tracing on anisotropic electron microscopy volume 期刊论文
Biomedical Signal Processing and Control, 2021, 卷号: 69, 期号: 无, 页码: 102829
作者:  Liu, Jing;  Hong, Bei;  Chen, Xi;  Xie, Qiwei;  Tang, Yuanyan;  Han, Hua
Adobe PDF(14559Kb)  |  收藏  |  浏览/下载：230/33  |  提交时间：2022/01/12
Neuron tracing  Electron microscopy  Deep learning  Convolutional LSTM  
An App knock-in rat model for Alzheimer's disease exhibiting A beta and tau pathologies, neuronal death and cognitive impairments 期刊论文
CELL RESEARCH, 2021, 页码: 19
作者:  Pang, Keliang;  Jiang, Richeng;  Zhang, Wei;  Yang, Zhengyi;  Li, Lin-Lin;  Shimozawa, Makoto;  Tambaro, Simone;  Mayer, Johanna;  Zhang, Baogui;  Li, Man;  Wang, Jiesi;  Liu, Hang;  Yang, Ailing;  Chen, Xi;  Liu, Jiazheng;  Winblad, Bengt;  Han, Hua;  Jiang, Tianzi;  Wang, Weiwen;  Nilsson, Per;  Guo, Wei;  Lu, Bai
收藏  |  浏览/下载：218/0  |  提交时间：2021/12/28
Levodopa Improves Cognitive Function and the Deficits of Structural Synaptic Plasticity in Hippocampus Induced by Global Cerebral Ischemia/Reperfusion Injury in Rats 期刊论文
FRONTIERS IN NEUROSCIENCE, 2020, 卷号: 14, 页码: 16
作者:  Wang, Wenzhu;  Liu, Xu;  Yang, Zhengyi;  Shen, Hui;  Liu, Lixu;  Yu, Yan;  Zhang, Tong
收藏  |  浏览/下载：184/0  |  提交时间：2021/03/02
levodopa  hippocampus  global cerebral ischemia reperfusion injury  structural synaptic plasticity  cognitive function  
Sparse self-attention aggregation networks for neural sequence slice interpolation 期刊论文
BioData Mining, 2021, 卷号: 14, 期号: 1, 页码: 19
作者:  Wang, Zejin;  Liu, Jing;  Chen, Xi;  Li, Guoqing;  Han, Hua
Adobe PDF(5022Kb)  |  收藏  |  浏览/下载：269/36  |  提交时间：2021/02/18
Slice interpolation  Biological tissue recovery  EM images  Sparse self-attention network  Adaptive style-balance loss