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Sensitive and quantitative in vivo analysis of PD‑L1 using magnetic particle imaging and imaging‑guided immunotherapy 期刊论文
European Journal of Nuclear Medicine and Molecular Imaging, 2022, 卷号: 50, 页码: 1291-1305
作者:  Zhengyao Peng;  Chang Lu;  Guangyuan Shi;  Lin Yin;  Xiaolong Liang;  Guosheng Song;  Jie Tian;  Yang Du
Adobe PDF(4924Kb)  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/05/28
DERnet: a deep neural network for end-to-end reconstruction in magnetic particle imaging 期刊论文
PHYSICS IN MEDICINE AND BIOLOGY, 2024, 卷号: 69, 期号: 1, 页码: 15
作者:  Peng, Zhengyao;  Yin, Lin;  Sun, Zewen;  Liang, Qian;  Ma, Xiaopeng;  An, Yu;  Tian, Jie;  Du, Yang
Adobe PDF(1035Kb)  |  收藏  |  浏览/下载：75/1  |  提交时间：2024/02/22
magnetic particle imaging  end-to-end reconstruction  deep learning  image reconstruction  
[68Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study 期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 11
作者:  Zhou, Ming;  Xiang, Shijun;  Zhao, Yajie;  Tang, Yongxiang;  Yang, Jinhui;  Yin, Xiaoqin;  Tian, Jie;  Hu, Shuo;  Du, Yang
收藏  |  浏览/下载：163/0  |  提交时间：2023/11/16
PD-1/PD-L1  Immune checkpoints  PET/CT imaging  Immunotherapy  
PD-L1 Aptamer-Functionalized Metal-Organic Framework Nanoparticles for Robust Photo-Immunotherapy against Cancer with Enhanced Safety 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 9
作者:  Zhang, Jingfang;  Li, Wenzhe;  Qi, Yafei;  Wang, Guorong;  Li, Lele;  Jin, Zhengyu;  Tian, Jie;  Du, Yang
收藏  |  浏览/下载：260/0  |  提交时间：2023/02/22
DNA Nanotechnology  Immunotherapy  Metal-Organic Frameworks  PD-L1 Aptamer  Spherical Nucleic Acids (SNAs)  
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors 期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:  Zhang,Pei;  Du,Yang;  Bai,Hua;  Wang,Zhijie;  Duan,Jianchun;  Wang,Xin;  Zhong,Jia;  Wan,Rui;  Xu,Jiachen;  He,Xiran;  Wang,Di;  Fei,Kailun;  Yu,Ruofei;  Tian,Jie;  Wang,Jie
收藏  |  浏览/下载：200/0  |  提交时间：2022/11/21
Tucidinostat  Tumor microenvironment  PD-L1  CCL5  Solid tumor  
A Fast and Automated FMT/XCT Reconstruction Strategy Based on Standardized Imaging Space 期刊论文
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2022, 卷号: 41, 期号: 3, 页码: 657-666
作者:  An, Yu;  Bian, Chang;  Yan, Daxiang;  Wang, Hanfan;  Wang, Yu;  Du, Yang;  Tian, Jie
Adobe PDF(8285Kb)  |  收藏  |  浏览/下载：316/61  |  提交时间：2022/06/06
Imaging  Image reconstruction  Mice  In vivo  Image segmentation  Finite element analysis  Surface reconstruction  Fluorescence molecular tomography  imaging reconstruction  standardized imaging space  
A Computational Prediction Method Based on Modified U-Net for Cell Distribution in Tumor Microenvironment 会议论文
, 线上会议, 2021-2-15
作者:  Bian, Chang;  Wang, Yu;  An, Yu;  Wang, Hanfan;  Du, Yang;  Tian, Jie
Adobe PDF(28768Kb)  |  收藏  |  浏览/下载：190/42  |  提交时间：2021/05/28
ImmunoAIzer: A Deep Learning-Based Computational Framework to Characterize Cell Distribution and Gene Mutation in Tumor Microenvironment 期刊论文
CANCERS, 2021, 卷号: 13, 期号: 7, 页码: 21
作者:  Bian, Chang;  Wang, Yu;  Lu, Zhihao;  An, Yu;  Wang, Hanfan;  Kong, Lingxin;  Du, Yang;  Tian, Jie
Adobe PDF(14076Kb)  |  收藏  |  浏览/下载：280/24  |  提交时间：2021/05/17
deep learning  cell distribution  biomarker  tumor gene mutation  tumor microenvironment (TME)  semi-supervised learning  hematoxylin and eosin (H&  E)  
A Hepatocellular Carcinoma Targeting Nanostrategy with Hypoxia-Ameliorating and Photothermal Abilities that, Combined with Immunotherapy, Inhibits Metastasis and Recurrence 期刊论文
ACS NANO, 2020, 卷号: 14, 期号: 10, 页码: 12679-12696
作者:  Zhou, Tianjun;  Liang, Xiaolong;  Wang, Peifeng;  Hu, Yueyang;  Qi, Yafei;  Jin, Yushen;  Du, Yang;  Fang, Chihua;  Tian, Jie
收藏  |  浏览/下载：206/0  |  提交时间：2021/03/02
hepatocellular carcinoma  prussian blue  photothermal therapy  sorafenib  hypoxia  antiprogrammed death-ligand I  immunotherapy  
Preclinical Study of a Dual Mode PD-L1 Target Imaging Probe Facilitates Patient Screening for Immunotherapy 期刊论文
JOURNAL OF NUCLEAR MEDICINE, 2020, 卷号: 61, 页码: 2
作者:  Ren, Jingyun;  Du, Yang;  Tian, Jie;  Huo, Li;  Li, Fang
收藏  |  浏览/下载：101/0  |  提交时间：2021/01/07