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Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors 期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
Authors:  Zhang,Pei;  Du,Yang;  Bai,Hua;  Wang,Zhijie;  Duan,Jianchun;  Wang,Xin;  Zhong,Jia;  Wan,Rui;  Xu,Jiachen;  He,Xiran;  Wang,Di;  Fei,Kailun;  Yu,Ruofei;  Tian,Jie;  Wang,Jie
Favorite  |  View/Download:6/0  |  Submit date:2022/11/21
Tucidinostat  Tumor microenvironment  PD-L1  CCL5  Solid tumor  
基于病理图像的细胞生物标志物表达预测算法研究 学位论文
, 中国科学院自动化研究所: 中国科学院自动化研究所, 2021
Authors:  边畅
Adobe PDF(22377Kb)  |  Favorite  |  View/Download:80/0  |  Submit date:2021/06/21
深度学习,半监督学习,细胞生物标志物,苏木精-伊红染色,多光谱免疫荧光染色,数字病理技术  
ImmunoAIzer: A Deep Learning-Based Computational Framework to Characterize Cell Distribution and Gene Mutation in Tumor Microenvironment 期刊论文
CANCERS, 2021, 卷号: 13, 期号: 7, 页码: 21
Authors:  Bian, Chang;  Wang, Yu;  Lu, Zhihao;  An, Yu;  Wang, Hanfan;  Kong, Lingxin;  Du, Yang;  Tian, Jie
Adobe PDF(14076Kb)  |  Favorite  |  View/Download:95/3  |  Submit date:2021/05/17
deep learning  cell distribution  biomarker  tumor gene mutation  tumor microenvironment (TME)  semi-supervised learning  hematoxylin and eosin (H&  E)  
A Computational Prediction Method Based on Modified U-Net for Cell Distribution in Tumor Microenvironment 会议论文
, 线上会议, 2021-2-15
Authors:  Bian, Chang;  Wang, Yu;  An, Yu;  Wang, Hanfan;  Du, Yang;  Tian, Jie
Adobe PDF(28768Kb)  |  Favorite  |  View/Download:56/2  |  Submit date:2021/05/28
Quantitative analysis of diffusion weighted imaging to predict pathological good response to neoadjuvant chemoradiation for locally advanced rectal cancer 期刊论文
RADIOTHERAPY AND ONCOLOGY, 2019, 卷号: 132, 页码: 100-108
Authors:  Tang, Zhenchao;  Zhang, Xiao-Yan;  Liu, Zhenyu;  Li, Xiao-Ting;  Shi, Yan-Jie;  Wang, Shou;  Fang, Mengjie;  Shen, Chen;  Dong, Enqing;  Sun, Ying-Shi;  Tian, Jie
Adobe PDF(2101Kb)  |  Favorite  |  View/Download:130/3  |  Submit date:2019/07/12
Locally advanced rectal cancer  Neoadjuvant chemoradiotherapy  Organ-preserving strategies  Diffusion weighted imaging  Decision support  
Advanced nanomaterials targeting hypoxia to enhance radiotherapy 期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2018, 卷号: 13, 页码: 5925-5936
Authors:  Jia Li;  Wenting Shang;  Yong Li;  Sirui Fu;  Jie Tian;  Ligong Lu
View  |  Adobe PDF(1988Kb)  |  Favorite  |  View/Download:181/28  |  Submit date:2018/10/10
radiotherapy  hypoxia  nanomaterials  hypoxia  inducible factor 1  
PD-1-IRDye800CW as a novel probe for fluorescence molecular imaging and image guided intraoperative surgery in breast tumor mouse model 期刊论文
CANCER RESEARCH, 2017, 卷号: 77
Authors:  Du, Y.;  Chi, C.;  Yang, X.;  Tian, J.
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Improved resection and prolonged overall survival with PD-1-IRDye800CW fluorescence probe-guided surgery and PD-1 adjuvant immunotherapy in 4T1 mouse model 期刊论文
INTERNATIONAL JOURNAL OF NANOMEDICINE, 2017, 卷号: 12, 期号: 12, 页码: 8337-8351
Authors:  Du, Yang;  Sun, Ting;  Liang, Xiaolong;  Li, Yuan;  Jin, Zhengyu;  Xue, Huadan;  Wan, Yihong;  Tian, Jie
View  |  Adobe PDF(4726Kb)  |  Favorite  |  View/Download:218/43  |  Submit date:2018/01/03
Pd-1  Programmed Cell Death-1  Near-infrared Fluorescence (Nirf)  Breast Cancer  Image-guided Surgery  Immunotherapy  Fluorescence Imaging