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eIF2α-mediated integrated stress response links multiple intracellular signaling pathways to reprogram vascular smooth muscle cell fate in carotid artery plaque 期刊论文
HELIYON, 2024, 卷号: 10, 期号: 5, 页码: 14
作者:  Luo, Jichang;  Zhang, Xiao;  Li, Wenjing;  Wang, Tao;  Cui, Shengyan;  Li, Tianhua;  Wang, Yilin;  Xu, Wenlong;  Ma, Yan;  Yang, Bin;  Luo, Yumin;  Yang, Ge;  Xu, Ran;  Jiao, Liqun
收藏  |  浏览/下载:5/0  |  提交时间:2024/07/03
Carotid artery atherosclerosis  Primary vascular smooth muscle cells  Organelles  Plaque vulnerability  Translation initiation factor 2 alpha  
A robust transformer-based pipeline of 3D cell alignment, denoise and instance segmentation on electron microscopy sequence images 期刊论文
Journal of Plant Physiology, 2024, 页码: 154236
作者:  Jiazheng, Liu;  Yafeng, Zheng;  Limei, Lin;  Jingyue, Guo;  Yanan, Lv;  Jingbin, Yuan;  Hao, Zhai;  Xi, Chen;  Lijun, Shen;  LinLin, Li;  Shunong, Bai;  Hua, Han
Adobe PDF(15549Kb)  |  收藏  |  浏览/下载:30/9  |  提交时间:2024/06/11
X-box Binding Protein 1: An Adaptor in the Pathogenesis of Atherosclerosis 期刊论文
AGING AND DISEASE, 2022, 页码: 20
作者:  Wang, Tao;  Zhou, Jia;  Zhang, Xiao;  Wu, Yujie;  Jin, Kehan;  Wane, Yilin;  Xu, Ran;  Yang, Ge;  Li, Wenjing;  Jiao, Liqun
收藏  |  浏览/下载:196/0  |  提交时间:2022/11/14
Endoplasmic Reticulum Stress  Unfolded Protein Response  XBP1  IRE1?  Atherosclerosis  
Deep Learning-Based Morphological Classification of Endoplasmic Reticulum Under Stress 期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 9, 页码: 13
作者:  Guo, Yuanhao;  Shen, Di;  Zhou, Yanfeng;  Yang, Yutong;  Liang, Jinzhao;  Zhou, Yating;  Li, Ningning;  Liu, Yu;  Yang, Ge;  Li, Wenjing
收藏  |  浏览/下载:226/0  |  提交时间:2022/03/17
ER stress  morphological classification  image biomarker  deep learning  homeostasis  
Three-dimensional ATUM-SEM reconstruction and analysis of hepatic endoplasmic reticulum-organelle interactions 期刊论文
JOURNAL OF MOLECULAR CELL BIOLOGY, 2021, 卷号: 13, 期号: 9, 页码: 636-645
作者:  Jiang, Yi;  Li, Linlin;  Chen, Xi;  Liu, Jiazheng;  Yuan, Jingbin;  Xie, Qiwei;  Han, Hua
Adobe PDF(1914Kb)  |  收藏  |  浏览/下载:347/50  |  提交时间:2022/01/27
3D reconstruction  ATUM-SEM  deep learning  liver  ER  MCSs  
Automatic Reconstruction of Mitochondria and Endoplasmic Reticulum in Electron Microscopy Volumes by Deep Learning 期刊论文
FRONTIERS IN NEUROSCIENCE, 2020, 期号: 14, 页码: 13
作者:  Liu, Jing;  Li, Linlin;  Yang, Yang;  Hong, Bei;  Chen, Xi;  Xie, Qiwei;  Han, Hua
浏览  |  Adobe PDF(1944Kb)  |  收藏  |  浏览/下载:322/75  |  提交时间:2020/09/21
mitochondria  endoplasmic reticulum  electron microscopes  segmentation  3D reconstruction  
Bioinformatics Methodologies to Identify Interactions Between Type 2 Diabetes and Neurological Comorbidities 期刊论文
IEEE ACCESS, 2019, 期号: 7, 页码: 183948-183970
作者:  Rahman, Md Habibur;  Peng, Silong;  Hu, Xiyuan;  Chen, Chen;  Uddin, Shahadat;  Quinn, Julian M. W.;  Moni, Mohammad Ali
浏览  |  Adobe PDF(9657Kb)  |  收藏  |  浏览/下载:348/45  |  提交时间:2020/03/30
Bioinformatics  comorbidities  gene set enrichment analysis  gene ontology  neurological disease  pathway  semantic similarity  Type 2 diabetes  
ApoG2 induces ER stress-dependent apoptosis in gastric cancer cells in vitro and its real-time evaluation by bioluminescence imaging in vivo 期刊论文
CANCER LETTERS, 2013, 卷号: 336, 期号: 2, 页码: 260-269
作者:  Xin, Jing;  Zhan, Yonghua;  Liu, Muhan;  Hu, Hao;  Xia, Limin;  Nie, Yongzhan;  Wu, Kaichun;  Liang, Jimin;  Tian, Jie;  Cancer Letters
浏览  |  Adobe PDF(2971Kb)  |  收藏  |  浏览/下载:446/142  |  提交时间:2015/08/12
Apog2  Gastric Cancer  Bioluminescence Imaging  Endoplasmic Reticulum Stress  
ApoG2 as the most potent gossypol derivatives inhibits cell growth and induces apoptosis on gastric cancer cells 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2013, 卷号: 67, 期号: 1, 页码: 88-95
作者:  Xin, J.;  Zhan, Y. H.;  Xia, L. M.;  Zhu, H. W.;  Nie, Y. Z.;  Liang, J. M.;  Tian, J.;  Tian, Jie
浏览  |  Adobe PDF(1544Kb)  |  收藏  |  浏览/下载:244/52  |  提交时间:2015/08/12
Apog2  Small-molecule Inhibitor  Gastric Cancer