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[68Ga]Ga-AUNP-12 PET imaging to assess the PD-L1 status in preclinical and first-in-human study 期刊论文
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2023, 页码: 11
作者:  Zhou, Ming;  Xiang, Shijun;  Zhao, Yajie;  Tang, Yongxiang;  Yang, Jinhui;  Yin, Xiaoqin;  Tian, Jie;  Hu, Shuo;  Du, Yang
收藏  |  浏览/下载：161/0  |  提交时间：2023/11/16
PD-1/PD-L1  Immune checkpoints  PET/CT imaging  Immunotherapy  
PD-L1 Aptamer-Functionalized Metal-Organic Framework Nanoparticles for Robust Photo-Immunotherapy against Cancer with Enhanced Safety 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 页码: 9
作者:  Zhang, Jingfang;  Li, Wenzhe;  Qi, Yafei;  Wang, Guorong;  Li, Lele;  Jin, Zhengyu;  Tian, Jie;  Du, Yang
收藏  |  浏览/下载：250/0  |  提交时间：2023/02/22
DNA Nanotechnology  Immunotherapy  Metal-Organic Frameworks  PD-L1 Aptamer  Spherical Nucleic Acids (SNAs)  
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors 期刊论文
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:  Zhang,Pei;  Du,Yang;  Bai,Hua;  Wang,Zhijie;  Duan,Jianchun;  Wang,Xin;  Zhong,Jia;  Wan,Rui;  Xu,Jiachen;  He,Xiran;  Wang,Di;  Fei,Kailun;  Yu,Ruofei;  Tian,Jie;  Wang,Jie
收藏  |  浏览/下载：198/0  |  提交时间：2022/11/21
Tucidinostat  Tumor microenvironment  PD-L1  CCL5  Solid tumor  
A Fast and Automated FMT/XCT Reconstruction Strategy Based on Standardized Imaging Space 期刊论文
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2022, 卷号: 41, 期号: 3, 页码: 657-666
作者:  An, Yu;  Bian, Chang;  Yan, Daxiang;  Wang, Hanfan;  Wang, Yu;  Du, Yang;  Tian, Jie
Adobe PDF(8285Kb)  |  收藏  |  浏览/下载：311/60  |  提交时间：2022/06/06
Imaging  Image reconstruction  Mice  In vivo  Image segmentation  Finite element analysis  Surface reconstruction  Fluorescence molecular tomography  imaging reconstruction  standardized imaging space  
ImmunoAIzer: A Deep Learning-Based Computational Framework to Characterize Cell Distribution and Gene Mutation in Tumor Microenvironment 期刊论文
CANCERS, 2021, 卷号: 13, 期号: 7, 页码: 21
作者:  Bian, Chang;  Wang, Yu;  Lu, Zhihao;  An, Yu;  Wang, Hanfan;  Kong, Lingxin;  Du, Yang;  Tian, Jie
Adobe PDF(14076Kb)  |  收藏  |  浏览/下载：276/23  |  提交时间：2021/05/17
deep learning  cell distribution  biomarker  tumor gene mutation  tumor microenvironment (TME)  semi-supervised learning  hematoxylin and eosin (H&  E)  
A Hepatocellular Carcinoma Targeting Nanostrategy with Hypoxia-Ameliorating and Photothermal Abilities that, Combined with Immunotherapy, Inhibits Metastasis and Recurrence 期刊论文
ACS NANO, 2020, 卷号: 14, 期号: 10, 页码: 12679-12696
作者:  Zhou, Tianjun;  Liang, Xiaolong;  Wang, Peifeng;  Hu, Yueyang;  Qi, Yafei;  Jin, Yushen;  Du, Yang;  Fang, Chihua;  Tian, Jie
收藏  |  浏览/下载：202/0  |  提交时间：2021/03/02
hepatocellular carcinoma  prussian blue  photothermal therapy  sorafenib  hypoxia  antiprogrammed death-ligand I  immunotherapy  
Preclinical Study of a Dual Mode PD-L1 Target Imaging Probe Facilitates Patient Screening for Immunotherapy 期刊论文
JOURNAL OF NUCLEAR MEDICINE, 2020, 卷号: 61, 页码: 2
作者:  Ren, Jingyun;  Du, Yang;  Tian, Jie;  Huo, Li;  Li, Fang
收藏  |  浏览/下载：96/0  |  提交时间：2021/01/07
Upfront dose-reduced chemotherapy synergizes with immunotherapy to optimize chemoimmunotherapy in squamous cell lung carcinoma 期刊论文
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 卷号: 8, 期号: 2, 页码: 15
作者:  He, Xiran;  Du, Yang;  Wang, Zhijie;  Wang, Xin;  Duan, Jianchun;  Wan, Rui;  Xu, Jiachen;  Zhang, Pei;  Wang, Di;  Tian, Yanhua;  Han, Jiefei;  Fei, Kailun;  Bai, Hua;  Tian, Jie;  Wang, Jie
收藏  |  浏览/下载：252/0  |  提交时间：2021/01/06
drug therapy  combination  immunotherapy  lung neoplasms  lymphocytes  tumor-infiltrating  translational medical research  
Noninvasive Imaging for Assessment of the Efficacy of Therapeutic Agents for Hepatocellular Carcinoma 期刊论文
Molecular Imaging and Biology, 2019, 期号: 10.1007/s11307-019-01431-5, 页码: 1-14
作者:  Liang, Qian;  Kong, Lingxin;  Zhu, Xu;  Du, Yang;  Tian, Jie
浏览  |  Adobe PDF(3951Kb)  |  收藏  |  浏览/下载：323/113  |  提交时间：2020/06/03
Hepatocellular carcinoma  Molecular imaging  Preclinical drug evaluation  Clinical trial  Therapeutics  
Combination Immunotherapy with Cytotoxic T-Lymphocyte-Associated Antigen-4 and Programmed Death Protein-1 Inhibitors Prevents Postoperative Breast Tumor Recurrence and Metastasis 期刊论文
MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 3, 页码: 802-811
作者:  Sun, Ting;  Zhang, Wenjia;  Li, Yuan;  Jin, Zhengyu;  Du, Yang;  Tian, Jie;  Xue, Huadan
收藏  |  浏览/下载：261/0  |  提交时间：2020/04/07